PMID- 8059523 OWN - NLM STAT- MEDLINE DCOM- 19940915 LR - 20161109 IS - 0507-4088 (Print) IS - 0507-4088 (Linking) VI - 38 IP - 2 DP - 1993 Mar-Apr TI - [The human herpesvirus type 6 (HHV-6) and its spread in Russia]. PG - 66-9 AB - This is the first presentation of information on the circulation of human herpes virus type 6 (HHV-6) in the population of the mid-European part of this country. The results of the study indicate that HHV-6 is widely spread both among apparently normal people and among patients with different pathologies. The studies using immunofluorescence test showed that the percentage of HHV-6-infected subjects was practically similar among blood donors, patients with nasopharyngeal cancer, rheumatoid arthritis, hemophilia, and patients with transplanted kidney, varying from 34% to 49%. A significantly higher per cent (66%) and higher antibody titres to HHV-6 were detected in sera from patients with hemoblastoses. A high level of HHV-6 infection among patients with hemoblastoses was also confirmed by the results of immunoblotting showing a wider spectrum and higher intensity of the detectable proteins. It should be noted that the amounts of virus-specific proteins detectable by some sera showed individual variations indicating different levels of expression of viral proteins in different individuals. FAU - Stepina, V N AU - Stepina VN FAU - Afanas'eva, T A AU - Afanas'eva TA FAU - Evtushenko, V V AU - Evtushenko VV FAU - Pivnik, A V AU - Pivnik AV FAU - Riashentsev, M M AU - Riashentsev MM FAU - Andreev, Iu N AU - Andreev IuN FAU - Kistoglu, Kh AU - Kistoglu Kh FAU - Gurtsevich, V E AU - Gurtsevich VE LA - rus PT - Comparative Study PT - English Abstract PT - Journal Article TT - Virus gerpesa cheloveka tipa 6 (HHV-6) i ego rasprostranenie v strane. PL - Russia (Federation) TA - Vopr Virusol JT - Voprosy virusologii JID - 0417337 RN - 0 (Antibodies, Viral) SB - IM MH - Antibodies, Viral/blood MH - Antibody Specificity MH - Arthritis, Rheumatoid/immunology MH - Blood Donors/statistics & numerical data MH - Hemophilia A/immunology MH - Herpesviridae Infections/epidemiology/immunology/microbiology MH - Herpesvirus 6, Human/immunology/*isolation & purification MH - Humans MH - Kidney Transplantation/immunology MH - Leukemia/immunology MH - Nasopharyngeal Neoplasms/immunology MH - Prevalence MH - Russia/epidemiology MH - Seroepidemiologic Studies EDAT- 1993/03/01 00:00 MHDA- 1993/03/01 00:01 CRDT- 1993/03/01 00:00 PHST- 1993/03/01 00:00 [pubmed] PHST- 1993/03/01 00:01 [medline] PHST- 1993/03/01 00:00 [entrez] PST - ppublish SO - Vopr Virusol. 1993 Mar-Apr;38(2):66-9.