PMID- 8069016
OWN - NLM
STAT- MEDLINE
DCOM- 19940929
LR  - 20190516
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 33
IP  - 4
DP  - 1994 Apr
TI  - An autopsy case of light chain deposition disease.
PG  - 216-21
AB  - This report describes a case of light chain deposition disease (LCDD) with 
      unusual findings of fibrillar structures in the deposits and marked calcification 
      in several organs. A forty-year-old man was initially diagnosed with LCDD in 
      1987, and died of sepsis three and one-half-years later. Histological examination 
      of autopsy specimens demonstrated eosinophilic amorphous materials, which 
      differed from amyloid, in vessel walls or around parenchymal cells in almost 
      every organ examined. Ultrastructurally, in addition to granular deposits, 
      fibrillar structures were also seen in the deposits. Marked calcification was 
      present in the myocardium, skeletal muscles, adrenal glands and arteries.
FAU - Kasahara, N
AU  - Kasahara N
AD  - Fourth Department of Internal Medicine, Saitama Medical School, Kawagoe.
FAU - Tamura, H
AU  - Tamura H
FAU - Matsumura, O
AU  - Matsumura O
FAU - Nagasawa, R
AU  - Nagasawa R
FAU - Suzuki, Y
AU  - Suzuki Y
FAU - Ohgida, T
AU  - Ohgida T
FAU - Itoyama, S
AU  - Itoyama S
FAU - Mitarai, T
AU  - Mitarai T
FAU - Isoda, K
AU  - Isoda K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Immunoglobulin Light Chains)
SB  - IM
MH  - Adrenal Glands/ultrastructure
MH  - Adult
MH  - Calcinosis
MH  - Humans
MH  - *Immunoglobulin Light Chains
MH  - Kidney/ultrastructure
MH  - Liver/ultrastructure
MH  - Male
MH  - Microscopy, Electron
MH  - Myocardium/ultrastructure
MH  - Paraproteinemias/*pathology
MH  - Spleen/ultrastructure
EDAT- 1994/04/01 00:00
MHDA- 1994/04/01 00:01
CRDT- 1994/04/01 00:00
PHST- 1994/04/01 00:00 [pubmed]
PHST- 1994/04/01 00:01 [medline]
PHST- 1994/04/01 00:00 [entrez]
AID - 10.2169/internalmedicine.33.216 [doi]
PST - ppublish
SO  - Intern Med. 1994 Apr;33(4):216-21. doi: 10.2169/internalmedicine.33.216.