PMID- 8069278
OWN - NLM
STAT- MEDLINE
DCOM- 19940927
LR  - 20220321
IS  - 0028-7091 (Print)
IS  - 0028-7091 (Linking)
VI  - 71
IP  - 1
DP  - 1994 Summer
TI  - Arthritis and mortality in the epidemiological follow-up to the National Health 
      and Nutrition Examination Survey I.
PG  - 69-86
AB  - Subsets were analyzed of respondents from the Epidemiological Follow-up to the 
      National Health and Nutrition Examination Survey I (NHANES I) who (1) answered a 
      general arthritis question reflecting whether a doctor told the respondent that 
      she or he had arthritis, (2) answered seven pain, swelling, and stiffness 
      questions, and (3) had radiographs of knees and hips assessed for osteoarthritis 
      at the time of the initial survey during the early 1970s. Data for the follow-up 
      were collected between 1982 and 1984 and included 1,491 fatalities in the largest 
      subsample analyzed here. The dependent variable was months of survival after the 
      initial interview. No distinction was drawn between rheumatoid arthritis versus 
      osteoarthritis. The NHANES I contained only limited information on rheumatoid 
      arthritis versus osteoarthritis. Additional covariates included age, age squared, 
      education, race, marital status, diastolic blood pressure, and body mass. After 
      adjusting for age, no statistically significant associations emerged between 
      answers to the general arthritis questions or any of the seven pain questions on 
      the one hand, and mortality on the other. Similar statistically insignificant 
      results were found when the association between radiographic diagnoses of 
      osteoarthritis in the hips and months of survival was considered after adjusting 
      for age. These statistically insignificant results persisted in repeated testing, 
      which alternately included and excluded a number of covariates, and in separate 
      subsamples of women, men, and persons older and younger than age 50. Some 
      evidence was found, however, for a negative, statistically significant 
      association between radiographic knee diagnoses of osteoarthritis and survival, 
      especially among women, even after adjusting for covariates. These mixed results 
      (1) do not discredit findings elsewhere suggesting that rheumatoid arthritis is 
      associated with early death, since it is likely that the great majority of 
      respondents answering in the affirmative to the general arthritis or seven pain 
      questions in the NHANES I had osteoarthritis, and (2) suggest that future surveys 
      should make greater attempts to distinguish between rheumatoid arthritis and 
      osteoarthritis.
FAU - Leigh, J P
AU  - Leigh JP
AD  - San Jose State University, CA 95192-0114.
FAU - Fries, J F
AU  - Fries JF
LA  - eng
GR  - AM21393/AM/NIADDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Bull N Y Acad Med
JT  - Bulletin of the New York Academy of Medicine
JID - 7505398
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Arthritis/diagnostic imaging/mortality
MH  - Arthritis, Rheumatoid/*mortality
MH  - Bias
MH  - Cause of Death
MH  - Child
MH  - Educational Status
MH  - Female
MH  - Follow-Up Studies
MH  - *Health Surveys
MH  - Humans
MH  - Male
MH  - Marital Status
MH  - Middle Aged
MH  - Osteoarthritis/*mortality
MH  - Radiography
MH  - Regression Analysis
MH  - Risk Factors
MH  - Sex Factors
PMC - PMC2359201
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
PMCR- 1994/06/01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
PHST- 1994/06/01 00:00 [pmc-release]
PST - ppublish
SO  - Bull N Y Acad Med. 1994 Summer;71(1):69-86.