PMID- 8069385
OWN - NLM
STAT- MEDLINE
DCOM- 19940923
LR  - 20190920
IS  - 1071-5762 (Print)
IS  - 1029-2470 (Linking)
VI  - 20
IP  - 5
DP  - 1994 May
TI  - The chemiluminescence assay of lipid peroxidation products in human blood plasma 
      lipoproteins.
PG  - 279-88
AB  - A chemiluminescence (CL) flash kinetics on the addition of Fe2+ ions into 
      oxidized low density lipoprotein (LDL) suspension has been studied. LDL oxidation 
      was carried out at 37 degrees C without and in the presence of 5 or 50 microM of 
      Cu2+. It has been found that under certain experimental conditions (the addition 
      of excess iron ions, more than 1 mM) the amplitude of CL flash depended almost 
      linearly (1) on the concentration of oxidized LDL and (2) on the extent of LDL 
      oxidation measured as diene conjugates (DC) and 2-thiobarbituric acid-reactive 
      substance (TBARS) accumulation. The corresponding correlation coefficients were: 
      for TBARS -0.94 and for DC -0.97, in the case of LDL autooxidation; 0.72 and 
      0.98, in the case of copper-induced LDL oxidation. A sensitivity of the CL method 
      was shown to be significantly enhanced (by more than two orders) in the presence 
      of CL sensitizer--2,3,5,6-1H,4H-tetrahydro-9-(2'-benzoimidazolyl)-qui 
      nolizin-(9,9a,1- gh)coumarin.
FAU - Driomina, E
AU  - Driomina E
AD  - Institute for Physical-Chemical Medicine, Moscow, Russia.
FAU - Polnikov, I
AU  - Polnikov I
FAU - Sharov, V
AU  - Sharov V
FAU - Azizova, O
AU  - Azizova O
FAU - Vladimirov, Y
AU  - Vladimirov Y
LA  - eng
PT  - Journal Article
PL  - England
TA  - Free Radic Res
JT  - Free radical research
JID - 9423872
RN  - 0 (Coloring Agents)
RN  - 0 (Coumarins)
RN  - 0 (Lipoproteins)
RN  - 0 (Lipoproteins, LDL)
RN  - 0 (Thiobarbituric Acid Reactive Substances)
RN  - 3K9958V90M (Ethanol)
RN  - A4VZ22K1WT (coumarin)
SB  - IM
MH  - Coloring Agents
MH  - Coumarins
MH  - Ethanol
MH  - Humans
MH  - Kinetics
MH  - *Lipid Peroxidation
MH  - Lipoproteins/*blood
MH  - Lipoproteins, LDL/blood
MH  - *Luminescent Measurements
MH  - Spectrophotometry
MH  - Thiobarbituric Acid Reactive Substances/analysis
EDAT- 1994/05/01 00:00
MHDA- 1994/05/01 00:01
CRDT- 1994/05/01 00:00
PHST- 1994/05/01 00:00 [pubmed]
PHST- 1994/05/01 00:01 [medline]
PHST- 1994/05/01 00:00 [entrez]
AID - 10.3109/10715769409145627 [doi]
PST - ppublish
SO  - Free Radic Res. 1994 May;20(5):279-88. doi: 10.3109/10715769409145627.