PMID- 8072352
OWN - NLM
STAT- MEDLINE
DCOM- 19940929
LR  - 20041117
IS  - 0023-852X (Print)
IS  - 0023-852X (Linking)
VI  - 104
IP  - 9
DP  - 1994 Sep
TI  - Allergic fungal sinusitis: the Mayo Clinic experience.
PG  - 1074-9
AB  - The diagnosis of allergic fungal sinusitis (AFS) is difficult to establish. The 
      clinical presentation is not diagnostic. We define current criteria for diagnosis 
      and the role of total and specific immunoglobulin E (IgE) and immunoglobulin G 
      (IgG) levels in the disease process and review the clinical features of this 
      disease. Fifty-one cases were identified in 44 patients who demonstrated 
      characteristic allergic mucin. Thirty-one of these cases satisfied rigid criteria 
      for the diagnosis of AFS. Twenty of these cases were classified as AFS-like 
      syndrome. The prevalence of strictly defined AFS was 4.0%. Dematiaceous fungi 
      were the predominant agents cultured. All our patients had polyps, 23 (54%) had 
      asthma, 12 (27%) had aspirin sensitivity, 20 (65%) had eosinophilia, and 9 (69%) 
      had increased total IgE levels.
FAU - Cody, D T 2nd
AU  - Cody DT 2nd
AD  - Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 55905.
FAU - Neel, H B 3rd
AU  - Neel HB 3rd
FAU - Ferreiro, J A
AU  - Ferreiro JA
FAU - Roberts, G D
AU  - Roberts GD
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Laryngoscope
JT  - The Laryngoscope
JID - 8607378
RN  - 0 (Antigens, Fungal)
RN  - 0 (Mucins)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Alternaria/isolation & purification
MH  - Antigens, Fungal/analysis
MH  - Eosinophils/pathology
MH  - Female
MH  - Humans
MH  - Hypersensitivity/*epidemiology/immunology/metabolism/pathology
MH  - Immunoglobulin E/analysis
MH  - Leukocyte Count
MH  - Male
MH  - Middle Aged
MH  - Minnesota/epidemiology
MH  - Mucins/analysis
MH  - Mycoses/*epidemiology/immunology/metabolism/pathology
MH  - Prevalence
MH  - Sinusitis/*epidemiology/immunology/metabolism/*microbiology/pathology
EDAT- 1994/09/01 00:00
MHDA- 2001/03/28 10:01
CRDT- 1994/09/01 00:00
PHST- 1994/09/01 00:00 [pubmed]
PHST- 2001/03/28 10:01 [medline]
PHST- 1994/09/01 00:00 [entrez]
AID - 10.1288/00005537-199409000-00005 [doi]
PST - ppublish
SO  - Laryngoscope. 1994 Sep;104(9):1074-9. doi: 10.1288/00005537-199409000-00005.