PMID- 8076342 OWN - NLM STAT- MEDLINE DCOM- 19941004 LR - 20190816 IS - 0165-4608 (Print) IS - 0165-4608 (Linking) VI - 76 IP - 1 DP - 1994 Aug TI - Two cases of t(1;16)(p11;p11) in multiple myeloma: confirmation by chromosome painting. PG - 10-4 AB - Two patients with multiple myeloma and an unbalanced translocation, t(1;16)(p11;p11), are reported. The fluorescence in situ hybridization (FISH) technique was used in one patient to confirm the translocation. To our knowledge, t(1;16)(p36;q13) and t(1;16)(q21;p13), but not t(1;16)(p11;p11), had been reported previously in multiple myeloma. Our results suggest that FISH is useful to characterize structural abnormalities and identify marker chromosomes in multiple myeloma where analysis with conventional cytogenetics is often difficult. FAU - Flactif, M AU - Flactif M AD - Laboratoire de Genetique Humaine et Pathologie Foetale, Faculte de Medecine, C.H.R.U., Lille, France. FAU - Lai, J L AU - Lai JL FAU - Zandecki, M AU - Zandecki M FAU - Bernardi, F AU - Bernardi F FAU - Trillot, N AU - Trillot N FAU - Bauters, F AU - Bauters F FAU - Facon, T AU - Facon T LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Cancer Genet Cytogenet JT - Cancer genetics and cytogenetics JID - 7909240 SB - IM MH - Aged MH - *Chromosomes, Human, Pair 1 MH - *Chromosomes, Human, Pair 16 MH - Female MH - Humans MH - In Situ Hybridization, Fluorescence MH - Karyotyping MH - Male MH - Middle Aged MH - Multiple Myeloma/*genetics MH - *Translocation, Genetic EDAT- 1994/08/01 00:00 MHDA- 1994/08/01 00:01 CRDT- 1994/08/01 00:00 PHST- 1994/08/01 00:00 [pubmed] PHST- 1994/08/01 00:01 [medline] PHST- 1994/08/01 00:00 [entrez] AID - 0165-4608(94)90061-2 [pii] AID - 10.1016/0165-4608(94)90061-2 [doi] PST - ppublish SO - Cancer Genet Cytogenet. 1994 Aug;76(1):10-4. doi: 10.1016/0165-4608(94)90061-2.