PMID- 8077029 OWN - NLM STAT- MEDLINE DCOM- 19941005 LR - 20131121 IS - 0019-6061 (Print) IS - 0019-6061 (Linking) VI - 30 IP - 12 DP - 1993 Dec TI - Maternal heart disease and perinatal outcome. PG - 1407-11 AB - Between January 1991 and August 1992, 62 singleton pregnancies with heart disease were managed at the Wadia Maternity Hospital, Bombay. In 51 (82.3%), the heart disease was of rheumatic origin, while in 11 (17.7%), the disease was nonrheumatic. Thirteen cases of rheumatic disease (25.4%) were graded as Class III or IV, as per New York Heart Association (NYHA) classification. Six cases with rheumatic disease had closed mitral commisurotomy done, while none had a prosthetic heart valve. There was no maternal mortality. The average birth weight of neonates born to mothers with Class III or IV rheumatic heart disease was significantly lower (p < 0.05) than the average noted in singleton, normal, uncomplicated, non high risk pregnancies, during this period. There was also a significant difference (p < 0.05) in birth weight between infants born to mothers with NYHA Class I or II and Class III or IV symptoms. No infant had a congenital heart disease. Our findings suggest that though the presence of maternal heart disease did not affect the perinatal outcome, all infants born to mothers with NYHA Class III or IV had intrauterine growth retardation. FAU - Mane, S V AU - Mane SV AD - Division of Obstetrics, Nowrosjee Wadia Maternity Hospital, Bombay. FAU - Gharpure, V P AU - Gharpure VP FAU - Merchant, R H AU - Merchant RH LA - eng PT - Comparative Study PT - Journal Article PL - India TA - Indian Pediatr JT - Indian pediatrics JID - 2985062R RN - 73K4184T59 (Digoxin) RN - 7LXU5N7ZO5 (Furosemide) RN - RWP5GA015D (Potassium) SB - IM MH - Adult MH - Digoxin/therapeutic use MH - Embryonic and Fetal Development MH - Female MH - Fetal Growth Retardation MH - Furosemide/therapeutic use MH - Gestational Age MH - Heart Diseases/drug therapy/*physiopathology MH - Humans MH - Infant, Low Birth Weight MH - Infant, Newborn MH - *Mothers MH - Potassium/therapeutic use MH - Pregnancy MH - Severity of Illness Index EDAT- 1993/12/01 00:00 MHDA- 1993/12/01 00:01 CRDT- 1993/12/01 00:00 PHST- 1993/12/01 00:00 [pubmed] PHST- 1993/12/01 00:01 [medline] PHST- 1993/12/01 00:00 [entrez] PST - ppublish SO - Indian Pediatr. 1993 Dec;30(12):1407-11.