PMID- 8083655
OWN - NLM
STAT- MEDLINE
DCOM- 19941013
LR  - 20220330
IS  - 0146-6615 (Print)
IS  - 0146-6615 (Linking)
VI  - 43
IP  - 1
DP  - 1994 May
TI  - Seroprevalence of antibodies to human herpesviruses in England and Hong Kong.
PG  - 91-6
AB  - The age-related prevalence of antibodies to herpesviruses was compared in England 
      and Hong Kong. Altogether 327 sera from England and 266 sera from Hong Kong were 
      tested for antibodies to herpes simplex virus (HSV), varicella-zoster virus 
      (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpesvirus 6 
      (HHV-6). Herpesvirus infections were common in both countries but generally were 
      acquired earlier and were more prevalent in Hong Kong. Over 90% of children in 
      Hong Kong were infected with VZV, EBV, and HHV-6 by 8 years of age. HSV and CMV 
      were the least prevalent childhood infections in both countries, although, 30-40% 
      of babies in Hong Kong became infected during the first year of life. CMV 
      infections were rare throughout childhood in the English cohort. Overcrowding and 
      early attendance at kindergarten may aid more efficient and earlier transmission 
      of herpesvirus in Hong Kong. The high prevalence of CMV in particular may have 
      implications for the management of young pregnant women and organ transplant 
      recipients in Hong Kong.
FAU - Kangro, H O
AU  - Kangro HO
AD  - Department of Virology, St. Bartholomew's Hospital Medical College, West 
      Smithfield, London, England.
FAU - Osman, H K
AU  - Osman HK
FAU - Lau, Y L
AU  - Lau YL
FAU - Heath, R B
AU  - Heath RB
FAU - Yeung, C Y
AU  - Yeung CY
FAU - Ng, M H
AU  - Ng MH
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Med Virol
JT  - Journal of medical virology
JID - 7705876
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Antibodies, Viral/*blood
MH  - Child
MH  - Child, Preschool
MH  - Cytomegalovirus/immunology
MH  - England/epidemiology
MH  - Herpesviridae/*immunology
MH  - Herpesvirus 3, Human/immunology
MH  - Herpesvirus 4, Human/immunology
MH  - Herpesvirus 6, Human/immunology
MH  - Hong Kong/epidemiology
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Simplexvirus/immunology
EDAT- 1994/05/01 00:00
MHDA- 1994/05/01 00:01
CRDT- 1994/05/01 00:00
PHST- 1994/05/01 00:00 [pubmed]
PHST- 1994/05/01 00:01 [medline]
PHST- 1994/05/01 00:00 [entrez]
AID - 10.1002/jmv.1890430117 [doi]
PST - ppublish
SO  - J Med Virol. 1994 May;43(1):91-6. doi: 10.1002/jmv.1890430117.