PMID- 8089199
OWN - NLM
STAT- MEDLINE
DCOM- 19941017
LR  - 20041117
IS  - 0730-2312 (Print)
IS  - 0730-2312 (Linking)
VI  - 55
IP  - 2
DP  - 1994 Jun
TI  - The ubiquitous nature of the progesterone receptor binding factor-1 (RBF-1) in 
      avian tissues.
PG  - 241-51
AB  - The avian oviduct receptor binding factor-1 (RBF-1) is a 10 kDa nuclear matrix 
      protein that was originally identified through its ability to effect high 
      affinity interaction of activated progesterone receptor (PR) with chromatin. In 
      the present study, the RBF-1 is shown to not be restricted to reproductive 
      tissues (e.g., oviduct) but present in all avian tissues examined by Western blot 
      analysis with a monoclonal antibody prepared against purified RBF-1. The heart 
      and pancreas had the highest and lowest RBF-1 levels, respectively; the 
      concentration ranging by approximately 50-fold in these tissues. The 10 kDa size 
      of the RBF-1 detected in all tissues suggests no significant tissue-specific 
      differences in the protein. This was consistent with the finding that purified 
      hepatic and oviductal RBF-1 have identical amino-terminal sequence. Using a 
      recently isolated cDNA to RBF-1, the levels of RBF-1 mRNA were found to correlate 
      well with the ubiquitous presence of the protein as well as tissue-specific 
      differences in concentration. The presence of RBF-1 in non-progesterone 
      responsive tissues suggests the possibility that RBF-1 may not be specifically 
      involved in PR-DNA interactions but may play a more diverse role, possibly 
      involving other steroid receptors such as the glucocorticoid receptor.
FAU - Landers, J P
AU  - Landers JP
AD  - Department of Biochemistry and Molecular Biology, Mayo Clinic/Foundation, 
      Rochester, Minnesota 55905.
FAU - Subramaniam, M
AU  - Subramaniam M
FAU - Gosse, B
AU  - Gosse B
FAU - Weinshilboum, R
AU  - Weinshilboum R
FAU - Madden, B J
AU  - Madden BJ
FAU - Spelsberg, T C
AU  - Spelsberg TC
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Cell Biochem
JT  - Journal of cellular biochemistry
JID - 8205768
RN  - 0 (Antibodies, Monoclonal)
RN  - 0 (Avian Proteins)
RN  - 0 (Carrier Proteins)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (RBF-1 protein, Gallus gallus)
RN  - 0 (RNA, Messenger)
RN  - 0 (Receptors, Progesterone)
SB  - IM
MH  - Amino Acid Sequence
MH  - Animals
MH  - Antibodies, Monoclonal
MH  - *Avian Proteins
MH  - Blotting, Western
MH  - Carrier Proteins/*analysis/genetics
MH  - *Chickens
MH  - Chromatography, Gel
MH  - Chromatography, High Pressure Liquid
MH  - DNA-Binding Proteins/*analysis/genetics
MH  - Electrophoresis, Polyacrylamide Gel
MH  - Liver/chemistry
MH  - Molecular Sequence Data
MH  - Oviducts/chemistry
MH  - RNA, Messenger/analysis
MH  - *Receptors, Progesterone
MH  - Tissue Distribution
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
AID - 10.1002/jcb.240550211 [doi]
PST - ppublish
SO  - J Cell Biochem. 1994 Jun;55(2):241-51. doi: 10.1002/jcb.240550211.