PMID- 8093669 OWN - NLM STAT- MEDLINE DCOM- 19930224 LR - 20190920 IS - 0886-0440 (Print) IS - 0886-0440 (Linking) VI - 8 IP - 1 DP - 1993 Jan TI - Bilateral internal mammary artery grafts in patients with left main coronary artery disease. PG - 18-24 AB - The use of the internal mammary artery (IMA) in myocardial revascularization has been expanded with bilateral and sequential grafting. However, its application in the presence of left main coronary artery stenosis (LMCAS) has not been well established. From September 1983 through December 1990, 280 patients with LMCAS greater than 50% were revascularized (3.4 mean grafts per patient) with bilateral IMA and saphenous vein grafts. Eighty-one were sequential IMA grafts. There were 234 males (83.6%) and 46 females (16.4%) with a mean age of 64.4 years (range 39 to 84 years). Preoperatively, there were six patients (2.1%) in New York Heart Association (NYHA) Class I, 30 patients (10.7%) in Class II, 130 patients (46.4%) in Class III, and 114 patients (40.7%) in Class IV. Fifty-six patients (20.0%) had an ejection fraction less than 50%. Intraaortic balloon counterpulsation was used preoperatively in 26 patients (9.3%) and intraoperatively in 11 patients (3.9%). There were four hospital deaths (1.4%). Hospital complications included: reoperation for bleeding, 7 patients (2.5%); pulmonary insufficiency, 21 patients (7.5%); perioperative infarction, 14 patients (5.0%); and stroke, 4 patients (1.4%). Follow-up was obtained in 276 hospital survivors (100.0%) with a mean of 33.4 months. There were 20 late deaths (7.1%): seven cardiac related and 12 noncardiac related. Postoperative assessment reveals substantial functional improvement. These results furnish evidence that bilateral IMA grafts can be accomplished with a low operative risk and can provide excellent functional results in patients with LMCAS. FAU - Galbut, D L AU - Galbut DL AD - Miami Heart Institute, Florida. FAU - Traad, E A AU - Traad EA FAU - Dorman, M J AU - Dorman MJ FAU - DeWitt, P L AU - DeWitt PL FAU - Larsen, P B AU - Larsen PB FAU - Kurlansky, P A AU - Kurlansky PA FAU - Carrillo, R G AU - Carrillo RG FAU - Gentsch, T O AU - Gentsch TO FAU - Galbut, B AU - Galbut B FAU - Ebra, G AU - Ebra G LA - eng PT - Journal Article PL - United States TA - J Card Surg JT - Journal of cardiac surgery JID - 8908809 SB - IM MH - Adult MH - Aged MH - Constriction, Pathologic/surgery MH - Coronary Disease/mortality/*surgery MH - Female MH - Follow-Up Studies MH - Hospital Mortality MH - Humans MH - Male MH - Middle Aged MH - *Myocardial Revascularization/mortality MH - Postoperative Complications MH - Saphenous Vein/transplantation MH - Survival Rate MH - Treatment Outcome EDAT- 1993/01/01 00:00 MHDA- 1993/01/01 00:01 CRDT- 1993/01/01 00:00 PHST- 1993/01/01 00:00 [pubmed] PHST- 1993/01/01 00:01 [medline] PHST- 1993/01/01 00:00 [entrez] AID - 10.1111/j.1540-8191.1993.tb00572.x [doi] PST - ppublish SO - J Card Surg. 1993 Jan;8(1):18-24. doi: 10.1111/j.1540-8191.1993.tb00572.x.