PMID- 8102984
OWN - NLM
STAT- MEDLINE
DCOM- 19930928
LR  - 20190821
IS  - 0020-7292 (Print)
IS  - 0020-7292 (Linking)
VI  - 41
IP  - 3
DP  - 1993 Jun
TI  - Human leukocyte antigen in hydatidiform mole.
PG  - 257-60
AB  - OBJECTIVE: To find any possible association between human leukocyte antigen (HLA) 
      as a genetic marker and the development of hydatidiform mole (HM). METHOD: The 
      lymphocyte microtoxicity technique was used to study the HLA antigens in 3 
      groups: 18 women with hydatidiform mole and their husbands (study group), 300 
      normal women (first control group), and 20 normal pregnant women and their 
      husbands (second control group). RESULT: Hydatidiform mole is more frequent in 
      women having HLA A1. The disease is more common in couples with partial 
      compatibility of the B locus. CONCLUSION: HM occurs more frequently in women with 
      certain HLA antigens and when the husband and wife have partial compatibility at 
      the B locus.
FAU - Souka, A R
AU  - Souka AR
AD  - Department of Obstetrics and Gynecology, Faculty of Medicine, University of 
      Alexandria, Egypt.
FAU - Kholeif, A
AU  - Kholeif A
FAU - Zaki, S
AU  - Zaki S
FAU - Rocca, M
AU  - Rocca M
FAU - Ghanem, I
AU  - Ghanem I
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Int J Gynaecol Obstet
JT  - International journal of gynaecology and obstetrics: the official organ of the 
      International Federation of Gynaecology and Obstetrics
JID - 0210174
RN  - 0 (Genetic Markers)
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
SB  - IM
MH  - Case-Control Studies
MH  - Cytotoxicity Tests, Immunologic
MH  - Female
MH  - Genetic Markers
MH  - HLA-A Antigens/*analysis
MH  - HLA-B Antigens/*analysis
MH  - Humans
MH  - Hydatidiform Mole/*genetics/immunology
MH  - Major Histocompatibility Complex
MH  - Male
MH  - Pregnancy
MH  - Uterine Neoplasms/*genetics/immunology
EDAT- 1993/06/01 00:00
MHDA- 1993/06/01 00:01
CRDT- 1993/06/01 00:00
PHST- 1993/06/01 00:00 [pubmed]
PHST- 1993/06/01 00:01 [medline]
PHST- 1993/06/01 00:00 [entrez]
AID - 10.1016/0020-7292(93)90552-8 [doi]
PST - ppublish
SO  - Int J Gynaecol Obstet. 1993 Jun;41(3):257-60. doi: 10.1016/0020-7292(93)90552-8.