PMID- 8103572
OWN - NLM
STAT- MEDLINE
DCOM- 19931004
LR  - 20221207
IS  - 0028-2804 (Print)
IS  - 0028-2804 (Linking)
VI  - 64
IP  - 7
DP  - 1993 Jul
TI  - ["Ecstasy"-induced psychotic depersonalization syndrome].
PG  - 478-80
AB  - The 'designer drug' 3,4-methylenedioxy-metamphetamine (MDMA; 'Ecstasy'), which 
      has become increasingly popular in the past few years, is supposed to induce a 
      feeling of euphoria with amphetamine-like stimulant effects. It was for some time 
      considered harmless, but neurotoxic effects on serotonergic neurons are now well 
      documented. To supplement case reports on different drug-induced 
      psychopathological and somatic complications published in recent literature, the 
      case of a 21-year-old female patient is reported, who exhibited a protracted 
      psychotic depersonalization disorder with suicidal tendency after the first 
      intake of two tablets of "ecstasy". In the course of six months the symptoms 
      remitted only gradually despite administration of a serotonin re-uptake 
      inhibitor, 'flash-backs' occurring repeatedly.
FAU - Wodarz, N
AU  - Wodarz N
AD  - Psychiatrische Klinik und Poliklinik, Universitat Wurzburg.
FAU - Boning, J
AU  - Boning J
LA  - ger
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
TT  - "Ecstasy"-induziertes psychotisches Depersonalisationssyndrom.
PL  - Germany
TA  - Nervenarzt
JT  - Der Nervenarzt
JID - 0400773
RN  - 0 (Designer Drugs)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - O26FZP769L (Lorazepam)
RN  - O4L1XPO44W (Fluvoxamine)
SB  - IM
CIN - Nervenarzt. 1994 Sep;65(9):648-50. PMID: 7991015
MH  - 3,4-Methylenedioxyamphetamine/adverse effects/*analogs & derivatives
MH  - Adult
MH  - Combined Modality Therapy
MH  - Depersonalization/*chemically induced/drug therapy/psychology
MH  - Designer Drugs/*adverse effects
MH  - Dose-Response Relationship, Drug
MH  - Female
MH  - Fluvoxamine/administration & dosage/adverse effects
MH  - Humans
MH  - Lorazepam/administration & dosage/adverse effects
MH  - N-Methyl-3,4-methylenedioxyamphetamine
MH  - Psychoses, Substance-Induced/drug therapy/*psychology
MH  - Suicide/psychology
MH  - Suicide Prevention
EDAT- 1993/07/01 00:00
MHDA- 1993/07/01 00:01
CRDT- 1993/07/01 00:00
PHST- 1993/07/01 00:00 [pubmed]
PHST- 1993/07/01 00:01 [medline]
PHST- 1993/07/01 00:00 [entrez]
PST - ppublish
SO  - Nervenarzt. 1993 Jul;64(7):478-80.