PMID- 8112256 OWN - NLM STAT- MEDLINE DCOM- 19940325 LR - 20190813 IS - 0013-9580 (Print) IS - 0013-9580 (Linking) VI - 35 IP - 1 DP - 1994 Jan-Feb TI - Nonconvulsive status epilepticus: EEG analysis in a large series. PG - 42-7 AB - We analyzed EEG characteristics comprehensively in a large series of nonconvulsive status epilepticus (NCSE) cases. Eighty-five ictal episodes in 78 patients were analyzed. The ictal discharges were generalized (group G) in 59 episodes (69%), diffuse with focal predominance (group GF) in 15 (18%), and focal (group F) in 11 (13%). The morphologies and patterns of persistence varied greatly. Frequency of ictal discharge was also variable and was almost always < 3 Hz. Demonstration of focal epileptic features in response to intravenous (i.v.) diazepam (DZP) and the presence of interictal focal epileptiform discharges in some cases in groups G and GF suggested possible focal onset secondarily generalized in these cases. This study suggests that electrographically NCSE is a highly heterogeneous epileptic state, and i.v. DZP may serve as a valuable diagnostic tool in differentiating generalized from focal onset NCSE. FAU - Granner, M A AU - Granner MA AD - Department of Neurology, University of Virginia Health Sciences Center, Charlottesville 22908. FAU - Lee, S I AU - Lee SI LA - eng PT - Journal Article PL - United States TA - Epilepsia JT - Epilepsia JID - 2983306R RN - Q3JTX2Q7TU (Diazepam) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Cerebral Cortex/physiopathology MH - Child MH - Child, Preschool MH - Diagnosis, Differential MH - Diazepam/pharmacology MH - *Electroencephalography/drug effects MH - Epilepsy, Complex Partial/diagnosis/physiopathology MH - Humans MH - Middle Aged MH - Status Epilepticus/classification/*diagnosis/physiopathology MH - Terminology as Topic EDAT- 1994/01/01 00:00 MHDA- 1994/01/01 00:01 CRDT- 1994/01/01 00:00 PHST- 1994/01/01 00:00 [pubmed] PHST- 1994/01/01 00:01 [medline] PHST- 1994/01/01 00:00 [entrez] AID - 10.1111/j.1528-1157.1994.tb02910.x [doi] PST - ppublish SO - Epilepsia. 1994 Jan-Feb;35(1):42-7. doi: 10.1111/j.1528-1157.1994.tb02910.x.