PMID- 8116255
OWN - NLM
STAT- MEDLINE
DCOM- 19940325
LR  - 20101118
IS  - 0042-6822 (Print)
IS  - 0042-6822 (Linking)
VI  - 199
IP  - 1
DP  - 1994 Feb 15
TI  - Genetic analysis and molecular phylogeny of simian T-cell lymphotropic virus type 
      I: evidence for independent virus evolution in Asia and Africa.
PG  - 56-66
AB  - Type C retroviruses, designated simian T-cell lymphotropic virus type I (STLV-I), 
      have been isolated from several genera of Old World monkeys and apes, but not 
      from New World monkeys and prosimians. To determine the genomic diversity and 
      molecular evolution of STLV-I and to clarify their genetic relationship to human 
      T-cell lymphotropic virus type I (HTLV-I), we enzymatically amplified, then 
      directly sequenced selected regions of the gag, pol, env, and pX genes of STLV-I 
      strains from Asia and Africa. STLV-I strains Si-2, Matsu, and JM86 from Japanese 
      macaques, which exhibited sequence similarities ranging from 98.5 to 99.8% among 
      themselves, diverged by 12.9 to 13.3% from STLV-I strain MM39-83 from a naturally 
      infected rhesus macaque, by 9.7 to 11.2% from STLV-I strains from Africa, and by 
      8.8 to 11.2% from HTLV-I strains originating in Japan, India, Africa, the 
      Caribbean, the Americas, Polynesia, and Melanesia. By contrast, the interspecies 
      nucleotide sequence similarity among African STLV-I strains from green monkey, 
      yellow baboon, sooty mangabey, and common chimpanzee was remarkably high, ranging 
      from 96.9 to 97.4%, and these STLV-I strains diverged by only 2.2 to 2.8% from 
      HTLV-I strain EL from equatorial Zaire. Phylogenetic trees constructed by using 
      the neighbor-joining and maximum parsimony methods indicated that the Asian 
      STLV-I strains diverged from the common ancestral virus prior to African STLV-I 
      and cosmopolitan and Melanesian HTLV-I strains. Thus, our data are consistent 
      with an archaic presence of STLV-I in Asia, probably predating macaque 
      speciation, with subsequent independent virus evolution in Asia and Africa.
FAU - Song, K J
AU  - Song KJ
AD  - Laboratory of Central Nervous System Studies, National Institute of Neurological 
      Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892.
FAU - Nerurkar, V R
AU  - Nerurkar VR
FAU - Saitou, N
AU  - Saitou N
FAU - Lazo, A
AU  - Lazo A
FAU - Blakeslee, J R
AU  - Blakeslee JR
FAU - Miyoshi, I
AU  - Miyoshi I
FAU - Yanagihara, R
AU  - Yanagihara R
LA  - eng
SI  - GENBANK/L20637
SI  - GENBANK/L20638
SI  - GENBANK/L20639
SI  - GENBANK/L20640
SI  - GENBANK/L20641
SI  - GENBANK/L20643
SI  - GENBANK/L20644
SI  - GENBANK/L20645
SI  - GENBANK/L20646
SI  - GENBANK/L20647
SI  - GENBANK/L20648
SI  - GENBANK/L20649
SI  - GENBANK/L20650
SI  - GENBANK/L20651
SI  - GENBANK/L20652
SI  - GENBANK/L20653
SI  - GENBANK/L20654
SI  - GENBANK/L20655
SI  - GENBANK/L20656
SI  - GENBANK/L20657
SI  - GENBANK/L20658
SI  - GENBANK/L20659
SI  - GENBANK/L20660
SI  - GENBANK/L20661
SI  - GENBANK/L20662
SI  - GENBANK/L20663
SI  - GENBANK/L20664
SI  - GENBANK/L20665
SI  - GENBANK/L20666
SI  - GENBANK/L20667
PT  - Journal Article
PL  - United States
TA  - Virology
JT  - Virology
JID - 0110674
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Africa
MH  - Animals
MH  - Asia
MH  - Base Sequence
MH  - *Biological Evolution
MH  - DNA, Viral
MH  - Humans
MH  - Molecular Sequence Data
MH  - Phylogeny
MH  - Primates
MH  - Sequence Homology, Nucleic Acid
MH  - Simian T-lymphotropic virus 1/classification/*genetics
EDAT- 1994/02/15 00:00
MHDA- 1994/02/15 00:01
CRDT- 1994/02/15 00:00
PHST- 1994/02/15 00:00 [pubmed]
PHST- 1994/02/15 00:01 [medline]
PHST- 1994/02/15 00:00 [entrez]
AID - S0042-6822(84)71097-X [pii]
AID - 10.1006/viro.1994.1097 [doi]
PST - ppublish
SO  - Virology. 1994 Feb 15;199(1):56-66. doi: 10.1006/viro.1994.1097.