PMID- 81193
OWN - NLM
STAT- MEDLINE
DCOM- 19781220
LR  - 20121115
IS  - 0146-0404 (Print)
IS  - 0146-0404 (Linking)
VI  - 17
IP  - 9
DP  - 1978 Sep
TI  - Localization of nervous system antigens in retina by immunohistology.
PG  - 920-4
AB  - Several antigens expressed in the nervous system were localized in tissue 
      sections of developing and adult mouse retina by indirect immunofluorescence. Two 
      antigens expressed in oligodendrocytes, basic protein of myelin, and NS-1 are not 
      detectable. Antisera against nervous system-3, -4, and -7 antigens (NS-3, NS-4, 
      and NS-7) give a uniformly intense reaction on all retinal cell structures. 
      Large, external, transformation-sensitive (LETS) protein is present on blood 
      vessels. Glial fibrillary acidic (GFA) protein is absent at birth but is found 
      after day 4 in cells of the ganglion cell and nerve fiber layers. GFA 
      protein--positive cells extend in parallel from inner to outer limiting membranes 
      only at the ora serrata and around the optic nerve. No other glial elements 
      contain GFA antigen, suggesting two distinct populations of astrocytes. 
      Neurofilament (NF) protein--positive cells are present in the adult retina in 
      outer plexiform and ganglion cell layers. By day 4 the ganglion cell layer and 
      the ependymal zone have become NF-positive.
FAU - Bromberg, J S
AU  - Bromberg JS
FAU - Schachner, M
AU  - Schachner M
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
RN  - 0 (Antigens)
RN  - 0 (Eye Proteins)
RN  - 0 (Myelin Basic Protein)
SB  - IM
MH  - Animals
MH  - Antigens/*isolation & purification
MH  - Eye Proteins/*immunology
MH  - Fluorescent Antibody Technique
MH  - Mice
MH  - Myelin Basic Protein/*immunology
MH  - Neuroglia/*immunology
MH  - Retina/cytology/*immunology
EDAT- 1978/09/01 00:00
MHDA- 1978/09/01 00:01
CRDT- 1978/09/01 00:00
PHST- 1978/09/01 00:00 [pubmed]
PHST- 1978/09/01 00:01 [medline]
PHST- 1978/09/01 00:00 [entrez]
PST - ppublish
SO  - Invest Ophthalmol Vis Sci. 1978 Sep;17(9):920-4.