PMID- 8127206
OWN - NLM
STAT- MEDLINE
DCOM- 19940412
LR  - 20220408
IS  - 0196-8092 (Print)
IS  - 0196-8092 (Linking)
VI  - 14
IP  - 1
DP  - 1994
TI  - Effect of low intensity laser (830 nm) irradiation on skin temperature and 
      antidromic conduction latencies in the human median nerve: relevance of radiant 
      exposure.
PG  - 40-6
AB  - The effects of low intensity near-infrared laser radiation (830 nm; 1.5-12 J/cm2; 
      continuous wave) on peripheral neurophysiology and skin temperature were 
      investigated using antidromic conduction studies in the human median nerve in 
      vivo. Healthy human volunteers (n = 80) were recruited and randomly allocated to 
      one of two control (n = 30) or five laser groups (1.5, 3.0, 6.0, 9.0, and 12 
      J/cm2; n = 10 per group). Analysis of variance (ANOVA) in negative peak latency 
      difference scores (NPLDs) and skin temperature over a 20 min period 
      post-irradiation demonstrated a significant decrease in skin temperature 
      following irradiation at the lowest radiant exposure (1.5 J/cm2) coupled with a 
      significant increase in NPLDs (P < 0.05). While no such (significant) changes 
      were found in the other laser groups, it was found that observed changes 
      (increases and decreases) in NPLDs were inversely related to changes in skin 
      temperature. These findings demonstrate measurable peripheral neurophysiological 
      effects of laser radiation concomitant with changes in skin temperature; however, 
      further studies are indicated to establish the precise relationship between the 
      observed effects on skin temperature and nerve conduction.
FAU - Lowe, A S
AU  - Lowe AS
AD  - Department of Biological and Biomedical Sciences, University of Ulster, 
      Jordanstown, Northern Ireland, United Kingdom.
FAU - Baxter, G D
AU  - Baxter GD
FAU - Walsh, D M
AU  - Walsh DM
FAU - Allen, J M
AU  - Allen JM
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Lasers Surg Med
JT  - Lasers in surgery and medicine
JID - 8007168
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Analysis of Variance
MH  - Female
MH  - Humans
MH  - *Lasers
MH  - Male
MH  - Median Nerve/*radiation effects
MH  - Neural Conduction/*radiation effects
MH  - Skin Temperature/*radiation effects
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
AID - 10.1002/lsm.1900140111 [doi]
PST - ppublish
SO  - Lasers Surg Med. 1994;14(1):40-6. doi: 10.1002/lsm.1900140111.