PMID- 8127656 OWN - NLM STAT- MEDLINE DCOM- 19940414 LR - 20190501 IS - 0305-1048 (Print) IS - 1362-4962 (Electronic) IS - 0305-1048 (Linking) VI - 22 IP - 1 DP - 1994 Jan 11 TI - A novel nuclear receptor superfamily member in Xenopus that associates with RXR, and shares extensive sequence similarity to the mammalian vitamin D3 receptor. PG - 66-71 AB - We report the isolation of xONR1, a novel member of the nuclear receptor superfamily from Xenopus laevis. xONR1 shares a high degree of amino acid sequence identity with the mammalian receptor for 1 alpha, 25-dihydroxy vitamin D3, particularly within the DNA-binding domain, although it does not bind this ligand. xONR1 DNA binding is stimulated by association with retinoid X receptor gamma (RXR gamma). FAU - Smith, D P AU - Smith DP AD - Department of Biological Sciences, University of Warwick, Coventry, UK. FAU - Mason, C S AU - Mason CS FAU - Jones, E A AU - Jones EA FAU - Old, R W AU - Old RW LA - eng SI - GENBANK/X75163 GR - Wellcome Trust/United Kingdom PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Nucleic Acids Res JT - Nucleic acids research JID - 0411011 RN - 0 (DNA Primers) RN - 0 (DNA, Complementary) RN - 0 (RNA, Messenger) RN - 0 (Receptors, Calcitriol) RN - 0 (Receptors, Cytoplasmic and Nuclear) RN - 0 (Receptors, Retinoic Acid) RN - 0 (Retinoid X Receptors) RN - 0 (Transcription Factors) RN - FXC9231JVH (Calcitriol) SB - IM GS - COUP GS - E75 GS - EAR1 GS - ERR2 GS - EcR GS - Knr1 GS - NF4 GS - ONR1 GS - PPAR&bgr; GS - RAR&ggr; GS - RXR&ggr; GS - TR&agr; GS - VDR MH - Age Factors MH - Amino Acid Sequence MH - Animals MH - Calcitriol/metabolism MH - Cloning, Molecular MH - DNA Primers/chemistry MH - DNA, Complementary/genetics MH - Gene Expression MH - Genes MH - Molecular Sequence Data MH - RNA, Messenger/genetics MH - Receptors, Calcitriol/*chemistry MH - Receptors, Cytoplasmic and Nuclear/chemistry/*genetics MH - *Receptors, Retinoic Acid MH - Retinoid X Receptors MH - Sequence Alignment MH - Sequence Homology, Amino Acid MH - *Transcription Factors MH - Xenopus laevis/embryology/*genetics MH - Zinc Fingers PMC - PMC307747 EDAT- 1994/01/11 00:00 MHDA- 1994/01/11 00:01 CRDT- 1994/01/11 00:00 PHST- 1994/01/11 00:00 [pubmed] PHST- 1994/01/11 00:01 [medline] PHST- 1994/01/11 00:00 [entrez] AID - 10.1093/nar/22.1.66 [doi] PST - ppublish SO - Nucleic Acids Res. 1994 Jan 11;22(1):66-71. doi: 10.1093/nar/22.1.66.