PMID- 8128802
OWN - NLM
STAT- MEDLINE
DCOM- 19940412
LR  - 20190914
IS  - 0514-7166 (Print)
IS  - 0514-7166 (Linking)
VI  - 40
IP  - 9-10
DP  - 1993 Dec
TI  - Serological studies on the potential synergism of porcine reproductive and 
      respiratory syndrome virus and influenza-, corona- and paramyxoviruses in the 
      induction of respiratory symptoms in swine.
PG  - 681-9
AB  - Sera from 265 finishing pigs belonging to 70 herds, in which severe respiratory 
      disorders were observed, were examined for antibody prevalence to porcine 
      reproductive and respiratory syndrome virus (PRRSV), influenza virus subtypes 
      H3N2 and H1N1, porcine respiratory corona virus (PRCV) and a recently described 
      porcine paramyxovirus (PPMV). By immunoperoxidase-monolayer assay 69.1% of these 
      sera were positive for PRRSV. Hemagglutination inhibiting activity was found in 
      55.1% of the sera for influenza virus subtype H1N1 (strain 
      A/swine/Arnsberg/1/81). in 51.3% for influenza virus subtype H3N2 (strain A/Hong 
      Kong/1/68) and in 14.3% for PPMV. PRCV specific antibodies, as determined by 
      differential competitive blocking enzyme-linked immunosorbent assay were 
      demonstrated in 192 of 236 (81.3%) sera. In order to reveal associations 
      interspecific coefficients were calculated for antibody prevalence between PRRSV 
      and the other viruses. Positive associations to PRRSV titres were found to PRCV, 
      PPMV and influenza virus subtype H1N1 titres. chi-square analysis showed the 
      statistical significance of associations regarding PRCV and influenza virus 
      subtype H1N1. Depletion of lung macrophages after PRRSV infection is discussed as 
      a possible mechanism for the promotion of secondary infections.
FAU - Groschup, M H
AU  - Groschup MH
AD  - Federal Research Centre for Virus Diseases of Animals, Tubingen, Germany.
FAU - Brun, A
AU  - Brun A
FAU - Haas, B
AU  - Haas B
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Zentralbl Veterinarmed B
JT  - Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. 
      Series B
JID - 0331325
SB  - IM
MH  - Animals
MH  - Arterivirus Infections/complications/veterinary
MH  - Coronavirus Infections/complications/veterinary
MH  - Orthomyxoviridae Infections/complications/veterinary
MH  - Respiratory Tract Infections/microbiology/*veterinary
MH  - Respirovirus Infections/complications/veterinary
MH  - Swine
MH  - Swine Diseases/*microbiology
MH  - Virus Diseases/microbiology/*veterinary
EDAT- 1993/12/01 00:00
MHDA- 1993/12/01 00:01
CRDT- 1993/12/01 00:00
PHST- 1993/12/01 00:00 [pubmed]
PHST- 1993/12/01 00:01 [medline]
PHST- 1993/12/01 00:00 [entrez]
AID - 10.1111/j.1439-0450.1993.tb00192.x [doi]
PST - ppublish
SO  - Zentralbl Veterinarmed B. 1993 Dec;40(9-10):681-9. doi: 
      10.1111/j.1439-0450.1993.tb00192.x.