PMID- 8134016
OWN - NLM
STAT- MEDLINE
DCOM- 19940415
LR  - 20190914
IS  - 0168-0102 (Print)
IS  - 0168-0102 (Linking)
VI  - 18
IP  - 1
DP  - 1993 Oct
TI  - Effects of differential rearing on the structure of perforated synapses in the 
      granule cell layer of the rat's accessory olfactory bulb.
PG  - 19-25
AB  - The effects of differential rearing on synaptic morphology in the granule cell 
      layer of the accessory olfactory bulb (AOB) were examined in adult rats. 
      Forty-day-old male rats were housed in one of three ways: individually (isolated 
      condition, IC); with four males per cage (unisexual condition, UC); or with two 
      males and two females per cage (social condition, SC). After 2 months, the 
      animals were killed for electron microscopy. Two types of synapses were 
      classified: (1) perforated synapses, which are characterized by discontinuities 
      in their postsynaptic thickenings, and (2) non-perforated synapses. The length of 
      the synaptic contact zone as well as the area and the length of the perimeter of 
      both the pre- and postsynaptic terminals were measured in each observed synapse. 
      For perforated synapses, the length of the synaptic contact zone was 
      significantly greater in the UC and the SC than in the IC. For the presynaptic 
      terminals of perforated synapses, the area was greater in the UC and the SC than 
      in the IC, and the length of the perimeter was greater in the UC than in the IC. 
      In contrast, there was no difference in the area and the length of the perimeter 
      among the three groups for postsynaptic terminals. For non-perforated synapses, 
      there was no statistically significant difference in either the area or the 
      length of the perimeter of pre- and postsynaptic terminals among the three 
      experimental groups, although the length of the synaptic contact zone was greater 
      in the SC than in the IC.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Ichikawa, M
AU  - Ichikawa M
AD  - Department of Anatomy and Embryology, Tokyo Metropolitan Institute for 
      Neuroscience, Japan.
FAU - Matsuoka, M
AU  - Matsuoka M
FAU - Mori, Y
AU  - Mori Y
LA  - eng
PT  - Journal Article
PL  - Ireland
TA  - Neurosci Res
JT  - Neuroscience research
JID - 8500749
SB  - IM
MH  - Analysis of Variance
MH  - *Animal Husbandry
MH  - Animals
MH  - Male
MH  - Microscopy, Electron
MH  - Nerve Endings/ultrastructure
MH  - Neuronal Plasticity
MH  - Olfactory Bulb/cytology/*ultrastructure
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - *Social Environment
MH  - Synapses/*ultrastructure
EDAT- 1993/10/01 00:00
MHDA- 1993/10/01 00:01
CRDT- 1993/10/01 00:00
PHST- 1993/10/01 00:00 [pubmed]
PHST- 1993/10/01 00:01 [medline]
PHST- 1993/10/01 00:00 [entrez]
AID - 0168-0102(93)90101-U [pii]
AID - 10.1016/0168-0102(93)90101-u [doi]
PST - ppublish
SO  - Neurosci Res. 1993 Oct;18(1):19-25. doi: 10.1016/0168-0102(93)90101-u.