PMID- 8135190 OWN - NLM STAT- MEDLINE DCOM- 19940418 LR - 20190512 IS - 0002-9173 (Print) IS - 0002-9173 (Linking) VI - 101 IP - 3 DP - 1994 Mar TI - Misleading hepatitis C serology following administration of intravenous immunoglobulin. PG - 327-8 AB - Intravenous immunoglobulin (IVIG) is a blood derivative that is being evaluated for the prevention and treatment of numerous disorders. Recent studies have suggested beneficial effects from the prophylactic administration of IVIG to very-low-birth-weight neonates. A disadvantage of such therapy is misleading infectious disease serologic assays following administration of IVIG. The authors report a recent case in their neonatal intensive care unit of a 24-week gestational age girl with a misleading positive hepatitis C serology reaction following IVIG administration. FAU - Nixon, R R AU - Nixon RR AD - Department of Pathology, Oregon Health Sciences University, Portland 97201-3042. FAU - Smith, S A AU - Smith SA FAU - Johnson, R L AU - Johnson RL FAU - Pillers, D A AU - Pillers DA LA - eng PT - Case Reports PT - Journal Article PL - England TA - Am J Clin Pathol JT - American journal of clinical pathology JID - 0370470 RN - 0 (Immunoglobulins) SB - IM MH - False Positive Reactions MH - Female MH - Hepatitis C/blood/*immunology MH - Humans MH - Immunoglobulins/*administration & dosage MH - *Infant, Low Birth Weight MH - Infant, Newborn MH - Injections, Intravenous EDAT- 1994/03/01 00:00 MHDA- 1994/03/01 00:01 CRDT- 1994/03/01 00:00 PHST- 1994/03/01 00:00 [pubmed] PHST- 1994/03/01 00:01 [medline] PHST- 1994/03/01 00:00 [entrez] AID - 10.1093/ajcp/101.3.327 [doi] PST - ppublish SO - Am J Clin Pathol. 1994 Mar;101(3):327-8. doi: 10.1093/ajcp/101.3.327.