PMID- 8143219
OWN - NLM
STAT- MEDLINE
DCOM- 19940505
LR  - 20080409
IS  - 0828-282X (Print)
IS  - 0828-282X (Linking)
VI  - 10
IP  - 2
DP  - 1994 Mar
TI  - Continuous wave Doppler measurements of aortic bloodflow during exercise in 
      patients with chronic heart failure.
PG  - 185-92
AB  - OBJECTIVE: To assess the feasibility of obtaining continuous wave Doppler 
      measurements of aortic bloodflow from the suprasternal notch during upright 
      treadmill exercise as an objective adjunct to cardiac performance and functional 
      capacity in heart failure. DESIGN: Prospective descriptive study. SETTING: 
      University teaching hospital out-patient heart failure clinic. PATIENTS: 
      Fifty-three patients with New York Heart Association (NYHA) class II or III heart 
      failure (left ventricular ejection fraction 9 to 37%) and 15 control subjects of 
      similar age but without heart disease. INTERVENTION: Symptom-limited (or to 
      completion of 22-min protocol) treadmill exercise using a modified Naughton 
      protocol. RESULTS: Exercise duration was 11.3 +/- 0.6 mins for heart failure and 
      20.5 +/- 0.6 mins for normals. Both within subject and interobserver variability 
      for the Doppler derived variables were satisfactory. There were no significant 
      differences at rest between groups for any of the measured Doppler variables. In 
      heart failure patients compared with normals, significant reductions in stroke 
      distance and peak velocity occurred during stage I and in peak acceleration 
      during stage II and persisted throughout exercise with reductions in maximum 
      achieved peak velocity (0.64 +/- 0.02 versus 0.97 +/- 0.05 m/s, P < 0.001), peak 
      acceleration (19.0 +/- 0.9 versus 37.3 +/- 2.4 m/s2, P < 0.001) and stroke 
      distance (7.5 +/- 0.3 versus 11.2 +/- 0.6 cm, P < 0.001). Receiver operator 
      curves had very favourable discriminating characteristics. No significant 
      differences in Doppler indices were observed between patients due to etiology of 
      heart failure or NYHA functional class. CONCLUSION: Aortic bloodflow indices can 
      be reliably measured from the suprasternal notch during upright treadmill 
      exercise in the majority of heart failure patients. Since the indices were 
      abnormal even at very early stages of exercise, further studies are required to 
      define their usefulness as an adjunct in the assessment of heart failure patients 
      whose maximum exercise tolerance is limited by other factors such as arthritis, 
      intermittent claudication or lung disease.
FAU - Arnold, J M
AU  - Arnold JM
AD  - Department of Medicine, Victoria Hospital, London, Ontario.
FAU - Cheung, P
AU  - Cheung P
FAU - Burton, G L
AU  - Burton GL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Can J Cardiol
JT  - The Canadian journal of cardiology
JID - 8510280
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aorta/*physiopathology
MH  - Cardiomyopathy, Dilated/complications
MH  - Chronic Disease
MH  - Coronary Disease/complications
MH  - Echocardiography, Doppler/*methods
MH  - Exercise Test/*methods
MH  - Feasibility Studies
MH  - Female
MH  - Heart Failure/classification/*diagnosis/etiology/*physiopathology
MH  - *Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Monitoring, Physiologic/methods
MH  - Observer Variation
MH  - Prospective Studies
MH  - Regional Blood Flow
MH  - Sensitivity and Specificity
MH  - Severity of Illness Index
MH  - Stroke Volume
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
PST - ppublish
SO  - Can J Cardiol. 1994 Mar;10(2):185-92.