PMID- 8152275
OWN - NLM
STAT- MEDLINE
DCOM- 19940506
LR  - 20130304
IS  - 0887-6924 (Print)
IS  - 0887-6924 (Linking)
VI  - 8 Suppl 1
DP  - 1994 Apr
TI  - An enhanced surveillance program for adult T-cell leukemia in central Brooklyn.
PG  - S111-5
AB  - The Brooklyn Adult T-cell Leukemia/Lymphoma (ATL) study was developed to estimate 
      the incidence of the human T-cell lymphotropic virus type I (HTLV-I)-associated 
      ATL in the Crown Heights/Bedford Stuyvesant community. This central Brooklyn 
      black community is an area which has already been shown in earlier reports to be 
      endemic for HTLV-I-associated ATL. Surveillance has been conducted at seven area 
      hospitals that serve this community, with surveillance already completed at five 
      hospitals. Potential study subjects who are 20 years or older are identified by 
      the review of admission records, discharge summaries, pathology and clinical 
      chemistry reports, or physician referrals. Diagnoses of leukemia or lymphoma, or 
      the presence of leukocytosis or hypercalcemia are used as criteria to identify 
      the subjects. Participating subjects give a sample of blood for the determination 
      of HTLV-I infection by serologic tests. At the time of enrollment, subjects 
      provide demographic information including age, sex and birthplace. After one year 
      of surveillance at five hospitals (39.5% of inpatient beds in the catchment), we 
      have identified 12 cases of HTLV-I-associated ATL. The mean age of the ATL 
      patients was 50 years, with patients being predominantly female (83.3%) and often 
      Caribbean immigrants (83.3%). Interestingly, 42% of our cases were identified 
      solely by findings of hypercalcemia from clinical chemistry reports. The 
      remaining ATL cases were identified by physician referral. This enhanced 
      surveillance program that uses both clinical and laboratory criteria for ATL case 
      ascertainment can serve as a prototype for similar surveillance in other areas 
      endemic for HTLV-I-associated ATL--an important effort because of the strong 
      potential for disease prevention.
FAU - Welles, S L
AU  - Welles SL
AD  - Department of Biostatistics, Harvard School of Public Health, Boston, MA.
FAU - Levine, P H
AU  - Levine PH
FAU - Joseph, E M
AU  - Joseph EM
FAU - Goberdhan, L J
AU  - Goberdhan LJ
FAU - Lee, S
AU  - Lee S
FAU - Miotti, A
AU  - Miotti A
FAU - Cervantes, J
AU  - Cervantes J
FAU - Bertoni, M
AU  - Bertoni M
FAU - Jaffe, E
AU  - Jaffe E
FAU - Dosik, H
AU  - Dosik H
LA  - eng
PT  - Journal Article
PL  - England
TA  - Leukemia
JT  - Leukemia
JID - 8704895
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Leukemia-Lymphoma, Adult T-Cell/diagnosis/*epidemiology
MH  - Male
MH  - Middle Aged
MH  - New York City/epidemiology
MH  - Population Surveillance
MH  - Referral and Consultation
EDAT- 1994/04/01 00:00
MHDA- 1994/04/01 00:01
CRDT- 1994/04/01 00:00
PHST- 1994/04/01 00:00 [pubmed]
PHST- 1994/04/01 00:01 [medline]
PHST- 1994/04/01 00:00 [entrez]
PST - ppublish
SO  - Leukemia. 1994 Apr;8 Suppl 1:S111-5.