PMID- 8156163
OWN - NLM
STAT- MEDLINE
DCOM- 19940513
LR  - 20191101
IS  - 0967-3849 (Print)
IS  - 0967-3849 (Linking)
VI  - 1
IP  - 4
DP  - 1993 Nov
TI  - Chromosomal localization of the lysozyme gene cluster in river buffalo (Bubalus 
      bubalis L.).
PG  - 253-5
AB  - Lysozyme (LYZ) is an antibacterial enzyme which allows the digestion of bacteria 
      present in tears and saliva. In the true stomach of ruminants LYZ breaks open the 
      bacteria of the foregut, which are subsequently digested by typical mammalian 
      digestive enzymes, allowing the incorporation of nutrients from the bacteria. 
      Southern analysis with a single exon from a cow lysozyme gene revealed that there 
      are about 10 genes in ruminants (Irwin & Wilson 1989), while pig and primates 
      have a single lysozyme gene (Swanson et al. 1991) and camels have two (Irwin et 
      al. 1992). The higher number of LYZ genes in ruminants is believed to be the 
      result of gene duplication associated with the evolution of foregut fermentation 
      (Irwin et al. 1992). Recently, the genomic organization of the lysozyme gene 
      family has been determined in domestic cattle, and, using a cocktail of genomic 
      clones, the lysozyme gene cluster (LYZ/) was assigned to chromosome (Chr) 5, band 
      23 by fluorescence in situ hybridization (FISH) (Gallagher et al. 1993). In our 
      continued effort to test the genetic homology of conserved chromosome banding 
      regions between cattle and river buffalo, and to extend the river buffalo 
      physical gene map, we have mapped the LYZ/ by FISH and R-banding.
FAU - Iannuzzi, L
AU  - Iannuzzi L
AD  - National Research Council (CNR), I.A.B.B.A.M., Naples-Ponticelli, Italy.
FAU - Gallagher, D S
AU  - Gallagher DS
FAU - Di Meo, G P
AU  - Di Meo GP
FAU - Ryan, A M
AU  - Ryan AM
FAU - Perucatti, A
AU  - Perucatti A
FAU - Ferrara, L
AU  - Ferrara L
FAU - Irwin, D M
AU  - Irwin DM
FAU - Womack, J E
AU  - Womack JE
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - Netherlands
TA  - Chromosome Res
JT  - Chromosome research : an international journal on the molecular, supramolecular 
      and evolutionary aspects of chromosome biology
JID - 9313452
RN  - 0 (Genetic Markers)
RN  - EC 3.2.1.17 (Muramidase)
SB  - IM
GS  - LYZ
MH  - Animals
MH  - Buffaloes/*genetics
MH  - Cattle
MH  - Chromosome Banding
MH  - Chromosome Mapping
MH  - Female
MH  - Genetic Markers
MH  - In Situ Hybridization, Fluorescence
MH  - *Multigene Family
MH  - Muramidase/*genetics
MH  - Species Specificity
EDAT- 1993/11/01 00:00
MHDA- 1993/11/01 00:01
CRDT- 1993/11/01 00:00
PHST- 1993/11/01 00:00 [pubmed]
PHST- 1993/11/01 00:01 [medline]
PHST- 1993/11/01 00:00 [entrez]
AID - 10.1007/BF00710130 [doi]
PST - ppublish
SO  - Chromosome Res. 1993 Nov;1(4):253-5. doi: 10.1007/BF00710130.