PMID- 8162990
OWN - NLM
STAT- MEDLINE
DCOM- 19940526
LR  - 20190821
IS  - 0903-1936 (Print)
IS  - 0903-1936 (Linking)
VI  - 7
IP  - 2
DP  - 1994 Feb
TI  - Aetiological agents in occupational asthma.
PG  - 346-71
AB  - Occupational asthma has become the most prevalent occupational lung disease in 
      developed countries. At present, about 200 agents have been implicated in causing 
      occupational asthma in the workplace. These agents can be divided into two 
      categories by their mechanism of action: immunological and nonimmunological. 
      Immunological causes can be further divided into those that induce asthma through 
      an immunoglobulin E (IgE)-dependent mechanism, and those that induce asthma 
      through a non-IgE-dependent mechanism. In the latter category, specific IgE 
      antibodies are found only in a small percentage of the patients with proven 
      disease, even though the clinical picture is compatible with an allergic 
      reaction. The immunological mechanism(s) responsible for these agents has yet to 
      be identified. The best known example of nonimmunological asthma is Reactive 
      Airways Dysfunction Syndrome (RADS) or irritant-induced asthma. In this review, 
      examples of types of agents causing occupational asthma are discussed and a 
      compendium table of aetiological agents is given.
FAU - Chan-Yeung, M
AU  - Chan-Yeung M
AD  - Dept of Medicine, Vancouver General Hospital, Canada.
FAU - Malo, J L
AU  - Malo JL
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Eur Respir J
JT  - The European respiratory journal
JID - 8803460
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
CIN - Eur Respir J. 1994 Sep;7(9):1727. PMID: 7995408
MH  - *Allergens
MH  - Animals
MH  - Asthma/epidemiology/*etiology
MH  - Humans
MH  - *Immunoglobulin E
MH  - Occupational Diseases/*etiology
MH  - Prevalence
RF  - 144
EDAT- 1994/02/01 00:00
MHDA- 1994/02/01 00:01
CRDT- 1994/02/01 00:00
PHST- 1994/02/01 00:00 [pubmed]
PHST- 1994/02/01 00:01 [medline]
PHST- 1994/02/01 00:00 [entrez]
AID - 10.1183/09031936.94.07020346 [doi]
PST - ppublish
SO  - Eur Respir J. 1994 Feb;7(2):346-71. doi: 10.1183/09031936.94.07020346.