PMID- 8172719
OWN - NLM
STAT- MEDLINE
DCOM- 19940609
LR  - 20190512
IS  - 1010-7940 (Print)
IS  - 1010-7940 (Linking)
VI  - 8
IP  - 2
DP  - 1994
TI  - Early and late results following combined coronary bypass surgery and mitral 
      valve replacement.
PG  - 57-62
AB  - To study the effect of various perioperative and operative variables, we analysed 
      the results of 66 consecutive patients undergoing mitral valve replacement (MVR) 
      and coronary artery bypass grafting (CABG). The mean age was 61.2 years (34 males 
      and 32 females), the mean follow-up 54.71 +/- 7.8 months. The hospital mortality 
      rate was 7.6% (5/66). New York Heart Association (NYHA) functional class (P < 
      0.01), left ventricular global wall motion score (increased scores indicating 
      impaired function, P = 0.005) and cross-clamp time (P < 0.05) were associated 
      with hospital mortality. There was no significant relationship of age (certainly 
      up to the age of 70), cause of mitral valve disease, severity of mitral 
      regurgitation, number of grafts, presence of angina, or previous myocardial 
      infarction with hospital mortality. There were eight late deaths, survival at 1, 
      3 and 5 years was 92.4%, 83.2% and 80.2%, respectively. Although there was a 
      trend for pulmonary vascular resistance (P = 0.15), NYHA class (P = 0.18) and 
      aortic cross-clamp time (P = 0.09) to be associated with late survival, the only 
      factor significantly related to late survival was global wall motion score (P = 
      0.001), i.e. those with scores of more than 10. Severity of mitral regurgitation 
      and cause of mitral valve disease have been reported as being related to late 
      survival in patients undergoing combined CABG and MVR, but we have found no such 
      relationship. Our results indicate that both hospital and late mortality after 
      this operation are strongly correlated with left ventricular function.
FAU - Ashraf, S S
AU  - Ashraf SS
AD  - Department of Cardiothoracic Surgery, Manchester Royal Infirmary, UK.
FAU - Shaukat, N
AU  - Shaukat N
FAU - Odom, N
AU  - Odom N
FAU - Keenan, D
AU  - Keenan D
FAU - Grotte, G
AU  - Grotte G
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Eur J Cardiothorac Surg
JT  - European journal of cardio-thoracic surgery : official journal of the European 
      Association for Cardio-thoracic Surgery
JID - 8804069
SB  - IM
MH  - Adult
MH  - Aged
MH  - Bioprosthesis
MH  - Cause of Death
MH  - Combined Modality Therapy
MH  - Coronary Angiography
MH  - *Coronary Artery Bypass
MH  - Female
MH  - Follow-Up Studies
MH  - *Heart Valve Prosthesis
MH  - Hemodynamics/*physiology
MH  - Hospital Mortality
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/physiopathology/*surgery
MH  - Myocardial Contraction/physiology
MH  - Postoperative Complications/mortality/*physiopathology
MH  - Prosthesis Design
MH  - Survival Rate
MH  - Ventricular Function, Left/physiology
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
AID - 10.1016/1010-7940(94)90091-4 [doi]
PST - ppublish
SO  - Eur J Cardiothorac Surg. 1994;8(2):57-62. doi: 10.1016/1010-7940(94)90091-4.