PMID- 8174080
OWN - NLM
STAT- MEDLINE
DCOM- 19940609
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 73
IP  - 1
DP  - 1994 Mar
TI  - Nonrandom changes of chromosome 10 in bladder cancer. Detection by FISH to 
      interphase nuclei.
PG  - 8-10
AB  - Fluorescence in situ hybridization (FISH) to interphase nuclei has been a 
      valuable method for examining the chromosome copies in tumor cells in clinical 
      practice. Twelve cases of transitional cell carcinoma (TCC) of the bladder were 
      investigated with a biotin-labeled repetitive DNA probe to detect numerical 
      aberrations of chromosome 10 in interphase nuclei. The cells containing one 
      fluorescent signal were screened in two of seven non-invasive tumors and in four 
      of five invasive tumors. Two patients presented two FISH spots of different 
      sizes. More than two signals were seen in one invasive tumor. The findings 
      suggest that partial or complete loss of a chromosome 10 is a nonrandom 
      aberration in bladder cancer.
FAU - Wang, M R
AU  - Wang MR
AD  - Laboratoire d'Histologie-Embryologie-Cytogenetique, Faculte de Medecine de 
      Clermont-Ferrand, France.
FAU - Perissel, B
AU  - Perissel B
FAU - Taillandier, J
AU  - Taillandier J
FAU - Kemeny, J L
AU  - Kemeny JL
FAU - Fonck, Y
AU  - Fonck Y
FAU - Lautier, A
AU  - Lautier A
FAU - Benkhalifa, M
AU  - Benkhalifa M
FAU - Malet, P
AU  - Malet P
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (DNA Probes)
SB  - IM
MH  - Carcinoma, Transitional Cell/*genetics/pathology
MH  - Cell Nucleus/ultrastructure
MH  - *Chromosome Aberrations
MH  - *Chromosomes, Human, Pair 10
MH  - DNA Probes
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Interphase
MH  - Urinary Bladder Neoplasms/*genetics/pathology
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
AID - 0165-4608(94)90175-9 [pii]
AID - 10.1016/0165-4608(94)90175-9 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1994 Mar;73(1):8-10. doi: 10.1016/0165-4608(94)90175-9.