PMID- 8175070 OWN - NLM STAT- MEDLINE DCOM- 19940609 LR - 20060623 IS - 0015-5659 (Print) IS - 0015-5659 (Linking) VI - 52 IP - 4 DP - 1993 TI - Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival. PG - 173-81 AB - In 1989 Leitbrock et al. reported the full primary structure of brain-derived neurotrophic factor. The messenger RNA for BDNF was found predominantly in the central nervous system, and the sequence of protein indicated its structural relation to NGF. BDNF belongs to a larger family of neurotrophic molecules. It stimulates the neurite outgrowth and supports neuronal survival. FAU - Wozniak, W AU - Wozniak W AD - Department of Anatomy, University Medical Academy, Poznan. LA - eng PT - Journal Article PT - Review PL - Poland TA - Folia Morphol (Warsz) JT - Folia morphologica JID - 0374620 RN - 0 (Brain-Derived Neurotrophic Factor) RN - 0 (Nerve Growth Factors) RN - 0 (Nerve Tissue Proteins) SB - IM MH - Animals MH - Brain-Derived Neurotrophic Factor MH - Cell Differentiation/physiology MH - Cell Survival/physiology MH - Nerve Growth Factors/*physiology MH - Nerve Tissue Proteins/*physiology MH - Neurons/*cytology RF - 68 EDAT- 1993/01/01 00:00 MHDA- 1993/01/01 00:01 CRDT- 1993/01/01 00:00 PHST- 1993/01/01 00:00 [pubmed] PHST- 1993/01/01 00:01 [medline] PHST- 1993/01/01 00:00 [entrez] PST - ppublish SO - Folia Morphol (Warsz). 1993;52(4):173-81.