PMID- 8187110 OWN - NLM STAT- MEDLINE DCOM- 19940621 LR - 20180215 IS - 0008-6312 (Print) IS - 0008-6312 (Linking) VI - 84 IP - 4-5 DP - 1994 TI - Noninvasive predictors of mortality for patients with Chagas' heart disease: a multivariate stepwise logistic regression study. PG - 261-7 AB - This prospective investigation was conducted in an attempt to identify noninvasive predictors of mortality for patients with Chagas' heart disease through a multivariate stepwise logistic regression study. Fifty-six patients with a positive complement fixation test for Chagas' disease were followed up at the Cardiomyopathy Clinic of our institution from April 1990 to April 1992. Patient age was 59 +/- 17 years; 28 (50%) were male. Upon admission, 19 patients (33%) were in the New York Heart Association (NYHA) class III and 8 (14%) in the NYHA class IV. Systolic blood pressure was 125 +/- 23 mm Hg, diastolic blood pressure 76 +/- 11 mm Hg and resting heart rate 77 +/- 11 beats/min. Forty patients (71%) were given digitalis and 39 (69%) angiotensin-converting enzyme inhibitors. Plasma Na+ was 140 +/- 4 mEq/l, K+ was 4.34 +/- 0.73 mEq/l and creatinine level 1.34 +/- 0.31 mg/100 ml. Cardiomegaly was observed in the chest X-ray of 41 of 51 (79%) available patients. Atrial fibrillation was observed in the resting ECG of 24 of 54 (44%) available patients, premature ventricular contractions in 23 (41%), right bundle branch block in 26 (46%) and left anterior hemiblock in 26 (46%) patients. Echocardiography revealed a left ventricular ejection fraction of 0.45 +/- 0.16, left ventricular systolic dimension of 51.23 +/- 13.53 mm and left ventricular diastolic dimension of 62.94 +/- 19 mm. Sixteen (28%) patients died during the 2-year study, 11 of them suddenly.(ABSTRACT TRUNCATED AT 250 WORDS) FAU - Bestetti, R B AU - Bestetti RB AD - Heart Institute, Santa Casa Hospital, Ribeirao Preto, Brazil. FAU - Dalbo, C M AU - Dalbo CM FAU - Freitas, O C AU - Freitas OC FAU - Teno, L A AU - Teno LA FAU - Castilho, O T AU - Castilho OT FAU - Oliveira, J S AU - Oliveira JS LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Switzerland TA - Cardiology JT - Cardiology JID - 1266406 SB - IM MH - Actuarial Analysis MH - Chagas Cardiomyopathy/drug therapy/*mortality/physiopathology MH - Female MH - Hemodynamics MH - Humans MH - *Logistic Models MH - Male MH - Middle Aged MH - Multivariate Analysis MH - Prognosis MH - Prospective Studies MH - Stroke Volume MH - Survival Analysis MH - Survivors EDAT- 1994/01/01 00:00 MHDA- 1994/01/01 00:01 CRDT- 1994/01/01 00:00 PHST- 1994/01/01 00:00 [pubmed] PHST- 1994/01/01 00:01 [medline] PHST- 1994/01/01 00:00 [entrez] AID - 10.1159/000176409 [doi] PST - ppublish SO - Cardiology. 1994;84(4-5):261-7. doi: 10.1159/000176409.