PMID- 8193933
OWN - NLM
STAT- MEDLINE
DCOM- 19940627
LR  - 20190719
IS  - 0361-9230 (Print)
IS  - 0361-9230 (Linking)
VI  - 34
IP  - 1
DP  - 1994
TI  - Vomeronasal organ-mediated induction of fos in the central accessory olfactory 
      pathways in repetitively mated female rats.
PG  - 53-9
AB  - Removal of the VNO significantly reduced the enhancement of lordosis and the 
      induction of fos immunoreactivity in luteinizing hormone-releasing hormone (LHRH) 
      neurons in ovariectomized estrogen-primed rats. There was a significant positive 
      correlation between the two variables. In the accessory olfactory bulb (AOB) of 
      the repetitively mated rats, the number of fos-positive cells in the granule (G) 
      cell layer was significantly lower in the VNO-removed rats, whereas that in the 
      mitral (M) cell layer was not significantly different between VNO-removed and 
      VNO-sham females. The G/M ratio (calculated by dividing the mean number of 
      fos-positive cells in the G cell layer by that in the M cell layer), taken as an 
      estimate of the output of the AOB, was relatively larger in the VN-sham as 
      compared with the VNO-removed rats. There were significant positive correlations 
      between G/M ratio and the increase in LQ and between the G/M ratio and the 
      percentage of fos-positive LHRH cells. The positive correlation between the 
      number of fos-positive cells in the posterodorsal medial amygdala (PDMA) and the 
      increase in LQ and that between the number of fos-positive cells in the PDMA and 
      the percentage of fos-positive LHRH cells were significant, supporting the role 
      of the medial nucleus of amygdala in lordosis. However, the correlation between 
      G/M ratio and the number of fos-positive cells in the PDMA was not significant, 
      indicating that fos immunoreactivity in the PDMA is not directly related to that 
      in the AOB.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Rajendren, G V
AU  - Rajendren GV
AD  - Department of Physiology, University of Texas Southwestern Medical Center at 
      Dallas, TX 75235-9040.
FAU - Moss, R L
AU  - Moss RL
LA  - eng
GR  - MH41784/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Brain Res Bull
JT  - Brain research bulletin
JID - 7605818
RN  - 0 (Estrogens)
RN  - 0 (Proto-Oncogene Proteins c-fos)
RN  - 33515-09-2 (Gonadotropin-Releasing Hormone)
SB  - IM
MH  - Amygdala/cytology/metabolism
MH  - Animals
MH  - *Copulation
MH  - Estrogens/pharmacology
MH  - Female
MH  - Gonadotropin-Releasing Hormone/metabolism
MH  - Immunohistochemistry
MH  - Male
MH  - Nasal Cavity/*physiology
MH  - Nasal Septum/*physiology
MH  - Neurons/metabolism/physiology
MH  - Olfactory Bulb/cytology/metabolism
MH  - Olfactory Pathways/*metabolism
MH  - Ovariectomy
MH  - Proto-Oncogene Proteins c-fos/*metabolism
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Sexual Behavior, Animal/physiology
EDAT- 1994/01/01 00:00
MHDA- 1994/01/01 00:01
CRDT- 1994/01/01 00:00
PHST- 1994/01/01 00:00 [pubmed]
PHST- 1994/01/01 00:01 [medline]
PHST- 1994/01/01 00:00 [entrez]
AID - 0361-9230(94)90186-4 [pii]
AID - 10.1016/0361-9230(94)90186-4 [doi]
PST - ppublish
SO  - Brain Res Bull. 1994;34(1):53-9. doi: 10.1016/0361-9230(94)90186-4.