PMID- 8194040
OWN - NLM
STAT- MEDLINE
DCOM- 19940624
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 74
IP  - 1
DP  - 1994 May
TI  - Identification of chromosomal structural alterations in human ovarian carcinoma 
      cells using combined GTG-banding and repetitive fluorescence in situ 
      hybridization (FISH).
PG  - 1-7
AB  - In order to identify chromosomal structural alterations in the ovarian carcinoma 
      cell line MLS/P, fluorescence in situ hybridization with centromeric probes for 
      chromosomes 1, 8, 9, 13/21, 14/22, 15, 17, and X and whole chromosome painting 
      probes for chromosomes 1, 3, 4, 5, 7, 8, 9, 10, 12, 13, 14, 17, 19, 22, and X 
      were performed subsequent to GTG-banding. This combined approach identified 14 of 
      the 18 clonal structurally rearranged chromosomes, with the X chromosome involved 
      in three aberrations. In contrast, only eight of the 14 rearrangements were 
      identifiable by G-banding alone. These results indicate that the combined 
      G-banding and FISH approach can significantly improve the cytogenetic analysis of 
      human neoplasia.
FAU - Xu, J
AU  - Xu J
AD  - Department of Pediatrics, University of Rochester School of Medicine and 
      Dentistry, New York 14642.
FAU - Wang, N
AU  - Wang N
LA  - eng
GR  - CA52761/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (Azure Stains)
SB  - IM
MH  - Azure Stains
MH  - Carcinoma/*genetics
MH  - *Chromosome Aberrations
MH  - Chromosome Banding
MH  - Female
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Ovarian Neoplasms/*genetics
MH  - Tumor Cells, Cultured
EDAT- 1994/05/01 00:00
MHDA- 1994/05/01 00:01
CRDT- 1994/05/01 00:00
PHST- 1994/05/01 00:00 [pubmed]
PHST- 1994/05/01 00:01 [medline]
PHST- 1994/05/01 00:00 [entrez]
AID - 0165-4608(94)90020-5 [pii]
AID - 10.1016/0165-4608(94)90020-5 [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1994 May;74(1):1-7. doi: 10.1016/0165-4608(94)90020-5.