PMID- 8196223
OWN - NLM
STAT- MEDLINE
DCOM- 19940624
LR  - 20110801
IS  - 0385-2385 (Print)
IS  - 0385-2385 (Linking)
VI  - 36
IP  - 3
DP  - 1994 Mar
TI  - [Prognosis and changes of peritoneal function in CAPD and APD patients].
PG  - 259-70
AB  - Prevention of peritoneal function is a major critical factor in the continuation 
      of CAPD treatment. Eighty-nine CAPD and APD patients were investigated for 7 
      years or 9 months, respectively. The purpose of the present study was (a) to 
      determine the levels of solute in the blood, i.e. serum creatinine (s-Cr), BUN, 
      hANP, Lp (a) and electrolytes, and urinary volume, water removal and dextrose 
      contents in the dialysate, and (b) to analyze these parameters according to 
      categories such as sex, age, presence of DM and frequency of peritonitis in such 
      patients. Peritoneal function of 15 APD patients was also examined by peritoneal 
      equilibration test (PET) and urea kinetics. Excretion of urine in female CAPD 
      patients was higher than that in male patients. The levels of BUN and s-Cr in 
      male CAPD patients increased gradually during the clinical course due to systemic 
      muscular volume and/or loss of urinary excretion. Although there were no 
      significant changes in the levels of solute in the blood between the ages of more 
      or less than 65 years of CAPD patients, the residual renal function rapidly 
      declined in patients more than 65 years of age. CAPD patients who had DM showed a 
      rapid decline in urinary volume, and an increase in Lp(a) and ultrafiltration. 
      The patients who had a frequent episode of peritonitis showed a decrease in water 
      removal with increase in the concentration of dextrose in dialysate. There was a 
      significant correlation between the levels of Ccr and those of KT/V in APD 
      patients after the correction of KT/V with dwell time of dialysate storage in the 
      abdominal cavity. It appears that several factors, such as sex, age, presence of 
      DM and frequency of peritonitis, may be important factors in the maintenance of 
      CAPD for long periods.
FAU - Yokoyama, K
AU  - Yokoyama K
AD  - Department of Medicine, Juntendo University, School of Medicine, Tokyo, Japan.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Jinzo Gakkai Shi
JT  - Nihon Jinzo Gakkai shi
JID - 7505731
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Female
MH  - Humans
MH  - Kidney Failure, Chronic/*physiopathology/therapy
MH  - Male
MH  - Middle Aged
MH  - *Peritoneal Dialysis
MH  - *Peritoneal Dialysis, Continuous Ambulatory
MH  - Peritoneum/*physiopathology
MH  - Prognosis
MH  - Sex Factors
EDAT- 1994/03/01 00:00
MHDA- 1994/03/01 00:01
CRDT- 1994/03/01 00:00
PHST- 1994/03/01 00:00 [pubmed]
PHST- 1994/03/01 00:01 [medline]
PHST- 1994/03/01 00:00 [entrez]
PST - ppublish
SO  - Nihon Jinzo Gakkai Shi. 1994 Mar;36(3):259-70.