PMID- 8203258
OWN - NLM
STAT- MEDLINE
DCOM- 19940707
LR  - 20190914
IS  - 0374-5600 (Print)
IS  - 0374-5600 (Linking)
VI  - 36
IP  - 2
DP  - 1994 Apr
TI  - Effect of specific immunotherapy in Dermatophagoides pteronyssinus allergic 
      children.
PG  - 150-2
AB  - The effect of immunotherapy on 21 Dermatophagoides pteronyssinus (Dpt)-sensitive 
      patients (15 children with extrinsic asthma and six children with extrinsic 
      asthma plus allergic rhinitis) aged 8.9 +/- 0.71 years was studied. Their 
      subjective and objective respiratory symptom score was recorded before beginning 
      and after the first year of immunotherapy. The respiratory subjective symptoms, 
      such as cough day/night, running nose, sputum production, sneezing, shortness of 
      breath at night and asthma attacks, decreased significantly from pretreatment 
      level (P < 0.05). The objective symptoms, such as wheezing, dyspnea with 
      prolonged expiration, sibilant rales and retractions score, gradually decreased 
      during treatment (P < 0.01). Total eosinophil count decreased in 76.2% of 
      patients after immunotherapy (P < 0.01). While total immunoglobulin E (IgE) 
      decreased in 81% of patients and specific IgE for Dpt decreased in 90.5% of 
      patients, specific IgG for Dpt increased in 76% of patient (P < 0.001). Our 
      results suggested that rising IgG and falling IgE values do not always coexist in 
      the patients who benefit from immunotherapy.
FAU - Koker, O
AU  - Koker O
AD  - Cukurova University, Department of Child Health, Adana, Turkey.
FAU - Guneser, S
AU  - Guneser S
FAU - Altintas, D
AU  - Altintas D
FAU - Kozanoglu, M
AU  - Kozanoglu M
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Acta Paediatr Jpn
JT  - Acta paediatrica Japonica : Overseas edition
JID - 0370357
SB  - IM
MH  - Adolescent
MH  - Animals
MH  - Asthma/*therapy
MH  - Child
MH  - Child, Preschool
MH  - Humans
MH  - *Immunotherapy
MH  - Mites/*immunology
MH  - Rhinitis, Allergic, Perennial/*therapy
EDAT- 1994/04/01 00:00
MHDA- 1994/04/01 00:01
CRDT- 1994/04/01 00:00
PHST- 1994/04/01 00:00 [pubmed]
PHST- 1994/04/01 00:01 [medline]
PHST- 1994/04/01 00:00 [entrez]
AID - 10.1111/j.1442-200x.1994.tb03151.x [doi]
PST - ppublish
SO  - Acta Paediatr Jpn. 1994 Apr;36(2):150-2. doi: 10.1111/j.1442-200x.1994.tb03151.x.