PMID- 8205707
OWN - NLM
STAT- MEDLINE
DCOM- 19940714
LR  - 20190623
IS  - 0009-7322 (Print)
IS  - 0009-7322 (Linking)
VI  - 89
IP  - 6
DP  - 1994 Jun
TI  - First use of an untethered, vented electric left ventricular assist device for 
      long-term support.
PG  - 2908-14
AB  - This report describes the first long-term (505-day) application of the vented 
      electric (VE) HeartMate left ventricular assist device (LVAD) (Thermo 
      Cardiosystems, Inc). The device consists of an abdominally placed, 
      battery-powered titanium blood pump that, in contrast to earlier pneumatically 
      powered systems, allows patients untethered freedom of movement. The batteries 
      last 5 to 8 hours and can be changed on a rotating basis indefinitely. The 
      patient, a 33-year-old man (90 kg, blood type O) with idiopathic cardiomyopathy, 
      experienced end-organ heart failure (New York Heart Association [NYHA] class IV) 
      while he was awaiting heart transplantation. When his hemodynamic criteria met 
      those outlined in the protocol, we implanted the VE-LVAD as a bridge to 
      transplantation. The patient was supported by the device for more than 16 months. 
      His cardiac status returned to NYHA class I, and he was eventually allowed to 
      take day trips outside the hospital as he awaited transplantation. The VE-LVAD 
      enabled the patient to participate in activities such as eating in restaurants, 
      going to movies, and practicing basketball shots. Unfortunately, the patient died 
      suddenly due to a neurological thromboembolic event that occurred on day 503 of 
      VE-LVAD support. The VE-LVAD improved native left ventricular function by chronic 
      unloading, and ventricular remodeling resulted in a more normal configuration 
      anatomically, physiologically, and ultimately, histologically and pathologically.
FAU - Frazier, O H
AU  - Frazier OH
AD  - Division of Cardiopulmonary Transplantation, Texas Heart Institute, St Luke's 
      Episcopal Hospital, Houston 77225-0345.
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Circulation
JT  - Circulation
JID - 0147763
SB  - IM
EIN - Circulation 1995 Jun 15;91(12):3026
MH  - Adult
MH  - Echocardiography, Transesophageal
MH  - Heart Transplantation
MH  - *Heart-Assist Devices
MH  - Humans
MH  - Male
EDAT- 1994/06/01 00:00
MHDA- 1994/06/01 00:01
CRDT- 1994/06/01 00:00
PHST- 1994/06/01 00:00 [pubmed]
PHST- 1994/06/01 00:01 [medline]
PHST- 1994/06/01 00:00 [entrez]
AID - 10.1161/01.cir.89.6.2908 [doi]
PST - ppublish
SO  - Circulation. 1994 Jun;89(6):2908-14. doi: 10.1161/01.cir.89.6.2908.