PMID- 8216746 OWN - NLM STAT- MEDLINE DCOM- 19931217 LR - 20031114 IS - 1001-652X (Print) IS - 1001-652X (Linking) VI - 36 IP - 8 DP - 1993 Aug TI - Effect of endothelin, angiotensin II and ANP on proliferation of vascular smooth muscle cells and cardiomyocytes. PG - 948-53 AB - By means of cell culture, 3H-thymidine (3H-TdR) incorporation and c-fos oncogene dot plotting technique, it was found that endothelin (ET) and angiotensin (ANG II) could promote proliferation and DNA synthesis of cultured vascular smooth muscle cells (VSMCs) and myocardial cells, and stimulate expression of c-fos oncogene of VSMCs. However, atrial natriuretic peptide (ANP) antagonizes the above effects of ET and ANG II. FAU - Wu, J M AU - Wu JM AD - Laboratory of Cardiopulmonary Endocrinology, Beijing Medical University, PRC. FAU - Cheng, T AU - Cheng T FAU - Sun, S D AU - Sun SD FAU - Niu, D D AU - Niu DD FAU - Zhang, J X AU - Zhang JX FAU - Wang, S H AU - Wang SH FAU - Tang, J AU - Tang J FAU - Tang, C S AU - Tang CS LA - eng PT - Journal Article PL - China TA - Sci China B JT - Science in China. Series B, Chemistry, life sciences & earth sciences JID - 8913082 RN - 0 (Endothelins) RN - 11128-99-7 (Angiotensin II) RN - 85637-73-6 (Atrial Natriuretic Factor) RN - 9007-49-2 (DNA) SB - IM GS - c-fos MH - Angiotensin II/*pharmacology MH - Animals MH - Aorta, Thoracic/cytology MH - Atrial Natriuretic Factor/*pharmacology MH - Cell Division/drug effects MH - Cells, Cultured MH - DNA/biosynthesis MH - Endothelins/*pharmacology MH - Gene Expression/drug effects MH - Genes, fos MH - Muscle, Smooth, Vascular/*cytology MH - Myocardium/cytology MH - Rabbits MH - Rats MH - Rats, Inbred SHR MH - Rats, Wistar EDAT- 1993/08/01 00:00 MHDA- 1993/08/01 00:01 CRDT- 1993/08/01 00:00 PHST- 1993/08/01 00:00 [pubmed] PHST- 1993/08/01 00:01 [medline] PHST- 1993/08/01 00:00 [entrez] PST - ppublish SO - Sci China B. 1993 Aug;36(8):948-53.