PMID- 8239780
OWN - NLM
STAT- MEDLINE
DCOM- 19931213
LR  - 20190514
IS  - 0003-4932 (Print)
IS  - 1528-1140 (Electronic)
IS  - 0003-4932 (Linking)
VI  - 218
IP  - 5
DP  - 1993 Nov
TI  - Small bowel obstruction after nephrectomy for Wilms' tumor. A report of the 
      National Wilms' Tumor Study-3.
PG  - 654-9
AB  - OBJECTIVE: This study was undertaken to define the incidence and etiology of 
      small bowel obstruction (SBO) after nephrectomy for Wilms' tumor. SUMMARY 
      BACKGROUND DATA: Intestinal obstruction is one of the most common postoperative 
      complications after nephrectomy for nephroblastoma. However, few reports have 
      evaluated risk factors for SBO. Radiation therapy has been associated with 
      increased intestinal complications in some adult cancer patients, but this has 
      not been reported in children undergoing cancer surgery. METHODS: Postoperative 
      SBO occurred in 131 of 1,910 children (6.9%) enrolled in the Third National 
      Wilms' Tumor Study (NWTS). The etiology of the SBO was bowel adhesions in 104 
      cases, intussusception in 17, internal hernia in 2, and uncertain in the 
      remaining 8 children. RESULTS: The factors found to be of potential importance in 
      explaining the incidence of SBO were higher local tumor stage, extrarenal 
      intravascular involvement, and en bloc resection of other organs at the time of 
      nephrectomy. The incidence of postoperative SBO was not increased in children who 
      received postoperative radiation therapy. CONCLUSIONS: Although the overall 
      incidence of SBO after nephrectomy for Wilms' tumor is comparable to that after 
      other major abdominal operations in children, it can be responsible for 
      significant morbidity. There were 4 children among the 1,910 patients with 
      infectious complications of SBO, which contributed to their death.
FAU - Ritchey, M L
AU  - Ritchey ML
AD  - Section of Urology, University of Michigan, Ann Arbor.
FAU - Kelalis, P P
AU  - Kelalis PP
FAU - Etzioni, R
AU  - Etzioni R
FAU - Breslow, N
AU  - Breslow N
FAU - Shochat, S
AU  - Shochat S
FAU - Haase, G M
AU  - Haase GM
LA  - eng
GR  - R01 CA054498/CA/NCI NIH HHS/United States
GR  - CA-42326/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Ann Surg
JT  - Annals of surgery
JID - 0372354
SB  - IM
MH  - Child, Preschool
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Incidence
MH  - Infant
MH  - Intestinal Obstruction/*epidemiology/*etiology
MH  - *Intestine, Small
MH  - Kidney Neoplasms/*epidemiology/*etiology
MH  - Male
MH  - Multivariate Analysis
MH  - Nephrectomy/*adverse effects
MH  - Radiotherapy/adverse effects
MH  - Risk Factors
MH  - Survival Rate
MH  - Wilms Tumor/radiotherapy/*surgery
PMC - PMC1243037
EDAT- 1993/11/01 00:00
MHDA- 1993/11/01 00:01
PMCR- 1993/11/01
CRDT- 1993/11/01 00:00
PHST- 1993/11/01 00:00 [pubmed]
PHST- 1993/11/01 00:01 [medline]
PHST- 1993/11/01 00:00 [entrez]
PHST- 1993/11/01 00:00 [pmc-release]
AID - 10.1097/00000658-199321850-00011 [doi]
PST - ppublish
SO  - Ann Surg. 1993 Nov;218(5):654-9. doi: 10.1097/00000658-199321850-00011.