PMID- 8242604
OWN - NLM
STAT- MEDLINE
DCOM- 19931230
LR  - 20190816
IS  - 0165-4608 (Print)
IS  - 0165-4608 (Linking)
VI  - 70
IP  - 2
DP  - 1993 Oct 15
TI  - Characterization of two marker chromosomes in a patient with acute nonlymphocytic 
      leukemia by two-color fluorescence in situ hybridization.
PG  - 99-102
AB  - A patient with acute nonlymphocytic leukemia (ANLL), M5b according to 
      French-American-British (FAB) classification, showed monosomy 16, an extra 1p-, 
      and a 21q+. These derivative chromosomes could not be defined by GTG-banding. For 
      better characterization, we performed two-color fluorescence in situ 
      hybridization (FISH) experiments applying DNA libraries from sorted human 
      chromosomes, chromosome-specific repetitive probes, and a band-specific 
      YAC-clone. With these FISH studies the karyotype could be characterized as 46,XY, 
      +der(1)t(1;21)(p11;?), -16,der(21)t(16;21) (p11.1;q22).
FAU - Taniwaki, M
AU  - Taniwaki M
AD  - Institut fur Humangenetik und Anthropologie, Universitat Heidelberg, Germany.
FAU - Speicher, M R
AU  - Speicher MR
FAU - Lengauer, C
AU  - Lengauer C
FAU - Jauch, A
AU  - Jauch A
FAU - Popp, S
AU  - Popp S
FAU - Cremer, T
AU  - Cremer T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cancer Genet Cytogenet
JT  - Cancer genetics and cytogenetics
JID - 7909240
RN  - 0 (DNA Probes)
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Adult
MH  - *Chromosome Aberrations
MH  - Chromosome Banding
MH  - Chromosomes, Artificial, Yeast
MH  - *Chromosomes, Human, Pair 1
MH  - *Chromosomes, Human, Pair 16
MH  - *Chromosomes, Human, Pair 21
MH  - DNA Probes
MH  - Gene Library
MH  - Genetic Markers
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Leukemia, Myeloid, Acute/*genetics
MH  - Male
MH  - Monosomy
MH  - Translocation, Genetic
EDAT- 1993/10/15 00:00
MHDA- 1993/10/15 00:01
CRDT- 1993/10/15 00:00
PHST- 1993/10/15 00:00 [pubmed]
PHST- 1993/10/15 00:01 [medline]
PHST- 1993/10/15 00:00 [entrez]
AID - 0165-4608(93)90175-L [pii]
AID - 10.1016/0165-4608(93)90175-l [doi]
PST - ppublish
SO  - Cancer Genet Cytogenet. 1993 Oct 15;70(2):99-102. doi: 
      10.1016/0165-4608(93)90175-l.