PMID- 8248736
OWN - NLM
STAT- MEDLINE
DCOM- 19931223
LR  - 20190914
IS  - 0029-845X (Print)
IS  - 0029-845X (Linking)
VI  - 101
IP  - 5
DP  - 1993 Oct
TI  - Mandibular condyle lesions related to age at onset and subtypes of juvenile 
      rheumatoid arthritis in 15-year-old children.
PG  - 332-8
AB  - The severity of lesions in the temporomandibular joint (TMJ) area and their 
      association with age at onset, the various forms of juvenile rheumatoid arthritis 
      (JRA), and certain serologic tests for rheumatoid factor (RF), antinuclear 
      antibodies (ANA), and human leukocyte antigen (HLA)-B27 were determined in 
      15-yr-old children. The series comprised 121 JRA children, 78 girls and 43 boys, 
      in whom an analysis had recently been made of the relation of TMJ lesions to jaw 
      movement and occlusal status. The mean age at onset was 7.3 yr, the girls 
      contracting JRA earlier than the boys. Also, the girls with lesions in the TMJ 
      area were significantly younger than those with no lesions. TMJ abnormalities 
      were found in 50% of cases with a pauciarticular or systemic onset, but in 72% of 
      those representing the polyarticular subtype. Flattened condyles and grave 
      lesions were equally represented in all subgroups and in both sexes. A crossover 
      from onset type to present diagnosis was found in 30% of the cases, mostly from 
      pauciarticular to polyarthritis, which also increased the risk of TMJ lesions 
      from 50 to 60%. RF, ANA, or HLA-B27 alone did not seem to be associated with a 
      risk of TMJ abnormalities. Maximal opening capacity is more restricted in 
      patients with early onset or a polyarticular mode of JRA. Since the TMJ is 
      affected in more than half of JRA children, regular measurements of maximal 
      movements of the mandible or roentgenologic examinations of the TMJ are essential 
      for their optimal treatment.
FAU - Karhulahti, T
AU  - Karhulahti T
AD  - Department of Oral Development and Orthodontics, University of Turku, Finland.
FAU - Ylijoki, H
AU  - Ylijoki H
FAU - Ronning, O
AU  - Ronning O
LA  - eng
PT  - Journal Article
PL  - Denmark
TA  - Scand J Dent Res
JT  - Scandinavian journal of dental research
JID - 0270023
RN  - 0 (HLA-B27 Antigen)
SB  - IM
MH  - Adolescent
MH  - Age Factors
MH  - Age of Onset
MH  - Arthritis, Juvenile/classification/immunology/*pathology/physiopathology
MH  - Female
MH  - HLA-B27 Antigen/analysis
MH  - Humans
MH  - Joints/pathology
MH  - Male
MH  - Mandible/physiopathology
MH  - Mandibular Condyle/*pathology/physiopathology
MH  - Movement
MH  - Sex Factors
MH  - Temporomandibular Joint Disorders/*pathology/physiopathology
EDAT- 1993/10/01 00:00
MHDA- 1993/10/01 00:01
CRDT- 1993/10/01 00:00
PHST- 1993/10/01 00:00 [pubmed]
PHST- 1993/10/01 00:01 [medline]
PHST- 1993/10/01 00:00 [entrez]
AID - 10.1111/j.1600-0722.1993.tb01128.x [doi]
PST - ppublish
SO  - Scand J Dent Res. 1993 Oct;101(5):332-8. doi: 10.1111/j.1600-0722.1993.tb01128.x.