PMID- 8254212 OWN - NLM STAT- MEDLINE DCOM- 19940110 LR - 20190821 IS - 0387-5911 (Print) IS - 0387-5911 (Linking) VI - 67 IP - 10 DP - 1993 Oct TI - [Methicillin resistance, production of toxic shock syndrome toxin-1 and types of enterotoxin, protease and coagulase at vaginal isolates of Staphylococcus aureus]. PG - 1005-10 AB - The vaginal colonization with Staphylococcus aureus, including strains that have methicillin resistance and production of toxic shock syndrome toxin-1 (TSST-1), enterotoxins and protease was studied in 308 women at the time of delivery. Thirty-six of these women were colonized with S. aureus in the vagina. All of the isolates were methicillin sensitive S. aureus (MSSA), except one women who had both methicillin resistant S. aureus (MRSA) and MSSA. The strains, included MRSA, did not elaborate the TSST-1 and produced protease. The distribution of protease pattern (types) observed by MSSA strains on standard methods caseinate agar plates was type A, 1 strain; type B, 15 strains; type C, 6 strains; type D, 14 strains. Sixteen of the 36 strains produced non of the enterotoxins and 20 strains produced enterotoxins and the type distribution was enterotoxin type A, 6 strains; type B, 10 strains; type C, 1 strain; A and B, 1 strain; A, B and C, 2 strains. These results provide the possibility of pathogenic S. aureus colonized in vagina transmit to neonates at the time of delivery. FAU - Arai, K AU - Arai K AD - Department of Microbiology, Yokohama City Institute of Health. FAU - Mitsuta, T AU - Mitsuta T FAU - Fujita, S AU - Fujita S FAU - Yokota, S AU - Yokota S LA - jpn PT - English Abstract PT - Journal Article PL - Japan TA - Kansenshogaku Zasshi JT - Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases JID - 0236671 RN - 0 (Bacterial Toxins) RN - 0 (Coagulase) RN - 0 (Enterotoxins) RN - 0 (Superantigens) RN - 0 (enterotoxin F, Staphylococcal) RN - EC 3.4.- (Endopeptidases) SB - IM MH - Adolescent MH - Adult MH - *Bacterial Toxins MH - Coagulase/*biosynthesis MH - Endopeptidases/*biosynthesis MH - Enterotoxins/*biosynthesis MH - Female MH - Humans MH - Labor, Obstetric MH - *Methicillin Resistance MH - Pregnancy MH - Staphylococcus aureus/drug effects/*metabolism MH - *Superantigens MH - Vagina/*microbiology EDAT- 1993/10/01 00:00 MHDA- 1993/10/01 00:01 CRDT- 1993/10/01 00:00 PHST- 1993/10/01 00:00 [pubmed] PHST- 1993/10/01 00:01 [medline] PHST- 1993/10/01 00:00 [entrez] AID - 10.11150/kansenshogakuzasshi1970.67.1005 [doi] PST - ppublish SO - Kansenshogaku Zasshi. 1993 Oct;67(10):1005-10. doi: 10.11150/kansenshogakuzasshi1970.67.1005.