PMID- 8254475 OWN - NLM STAT- MEDLINE DCOM- 19940107 LR - 20200220 IS - 0894-9255 (Print) IS - 0894-9255 (Linking) VI - 6 IP - 12 DP - 1993 Dec TI - Demographic characteristics of retroviral infections (HIV-1, HIV-2, and HTLV-I) among female professional sex workers in Lagos, Nigeria. PG - 1358-63 AB - In 1990/1991, 885 prostitutes residing in 11 of the 12 Local Government Areas (LGAs) of Lagos State, Nigeria, participated in a cross-sectional study to determine current seroprevalence of antibodies to human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2), and human T-cell lymphotropic virus type I (HTLV-I). The overall prevalence of HIV-1 was 12.3%, of HIV-2, 2.1%, and of HTLV-I, 2.8%. HIV-1 seropositivity did not vary significantly by age, socioeconomic class, or nationality, but HIV-1 seroprevalence was significantly elevated for prostitutes resident in the Port area of Lagos which serves as a crossroads for international and national commerce (OR = 2.3; 95% CI = 1.1, 4.6). HIV-2 infection was significantly associated with low socioeconomic class (OR = 3.7; 95% CI = 1.2, 10.8) and non-Nigerian nationality (OR = 6.7; 95% CI = 2.5, 18.4). Prevalence of HTLV-I infection increased significantly with age (OR = 2.3; 95% CI = 1.0, 5.3). The high seroprevalence of HIV-1 in this survey, compared with previous surveys reported in the last several years and the correlation between high prevalence and areas of international commerce suggest that HIV-1 is spreading in this area of Nigeria. Intensified prevention campaigns are needed to address this possible emerging epidemic. FAU - Dada, A J AU - Dada AJ AD - Research Triangle Institute, Washington, DC. FAU - Oyewole, F AU - Oyewole F FAU - Onofowokan, R AU - Onofowokan R FAU - Nasidi, A AU - Nasidi A FAU - Harris, B AU - Harris B FAU - Levin, A AU - Levin A FAU - Diamondstone, L AU - Diamondstone L FAU - Quinn, T C AU - Quinn TC FAU - Blattner, W A AU - Blattner WA LA - eng GR - N01-CP-85603/CP/NCI NIH HHS/United States GR - N01-CP-95612/CP/NCI NIH HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - J Acquir Immune Defic Syndr (1988) JT - Journal of acquired immune deficiency syndromes JID - 8812597 RN - 0 (HIV Antibodies) RN - 0 (HTLV-I Antibodies) SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - Cross-Sectional Studies MH - Female MH - HIV Antibodies/blood MH - HIV Infections/*epidemiology MH - HIV Seroprevalence MH - HIV-1/*immunology MH - HIV-2/*immunology MH - HTLV-I Antibodies/blood MH - HTLV-I Infections/*epidemiology MH - Humans MH - Middle Aged MH - Nigeria/epidemiology MH - Prevalence MH - *Sex Work MH - Social Class MH - Urban Population EDAT- 1993/12/01 00:00 MHDA- 1993/12/01 00:01 CRDT- 1993/12/01 00:00 PHST- 1993/12/01 00:00 [pubmed] PHST- 1993/12/01 00:01 [medline] PHST- 1993/12/01 00:00 [entrez] PST - ppublish SO - J Acquir Immune Defic Syndr (1988). 1993 Dec;6(12):1358-63.