PMID- 8259312
OWN - NLM
STAT- MEDLINE
DCOM- 19940119
LR  - 20041117
IS  - 0030-932X (Print)
IS  - 0030-932X (Linking)
VI  - 31
IP  - 4
DP  - 1993
TI  - Pre- and perinatal infections due to human herpesvirus-6 and Epstein-Barr-virus 
      with lethal outcome or severe residual encephalopathy.
PG  - 199-201
AB  - The Human Herpesvirus-6 (HHV-6) infection causes exanthem subitum (in typical 
      cases) and a wide range of other symptoms. So far no prenatal or perinatal 
      infections have been reported. For HHV-6 the prenatal infection should be 
      extremely rare, because more than 95% of adults are immune in Germany. Two own 
      cases reported here document that pre- and perinatal HHV-6 infection does occur 
      and can provoke dramatic clinical symptoms of illness with death or cerebral 
      defects like other prenatal herpesvirus infections (HSV, VZV, CMV etc.).
FAU - Wiersbitzky, S
AU  - Wiersbitzky S
AD  - Department of Pediatrics, Ernst-Moritz-Arndt-University, Greifswald, Germany.
FAU - Beyersdorf, E
AU  - Beyersdorf E
FAU - Burtzlaff, C
AU  - Burtzlaff C
FAU - Wiersbitzky, H
AU  - Wiersbitzky H
FAU - Crusius, S
AU  - Crusius S
FAU - Weinke, I
AU  - Weinke I
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Padiatr Grenzgeb
JT  - Padiatrie und Grenzgebiete
JID - 0401115
RN  - 0 (Antibodies, Bacterial)
SB  - IM
MH  - Antibodies, Bacterial/analysis
MH  - Brain Damage, Chronic/diagnosis/immunology
MH  - Encephalitis/*diagnosis/immunology
MH  - Exanthema Subitum/*diagnosis/immunology
MH  - Female
MH  - Follow-Up Studies
MH  - Herpesviridae Infections/*diagnosis/immunology
MH  - Herpesvirus 4, Human/*immunology
MH  - Herpesvirus 6, Human/*immunology
MH  - Humans
MH  - Immunity, Maternally-Acquired/immunology
MH  - Infant
MH  - Infant, Newborn
MH  - Male
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*diagnosis/immunology
MH  - Viremia/*diagnosis/immunology
EDAT- 1993/01/01 00:00
MHDA- 1993/01/01 00:01
CRDT- 1993/01/01 00:00
PHST- 1993/01/01 00:00 [pubmed]
PHST- 1993/01/01 00:01 [medline]
PHST- 1993/01/01 00:00 [entrez]
PST - ppublish
SO  - Padiatr Grenzgeb. 1993;31(4):199-201.