PMID- 8260484
OWN - NLM
STAT- MEDLINE
DCOM- 19940124
LR  - 20190719
IS  - 0007-1145 (Print)
IS  - 0007-1145 (Linking)
VI  - 70
IP  - 2
DP  - 1993 Sep
TI  - Interrelationship between vitamin A, iodine and iron status in schoolchildren in 
      Shoa Region, central Ethiopia.
PG  - 593-607
AB  - A total of 14,740 schoolchildren in seven provinces of Shoa Administrative Region 
      in Central Ethiopia were surveyed for the prevalence of goitre, xerophthalmia and 
      anaemia. Haemoglobin and packed cell volume were assessed in 966 children in one 
      province while an in-depth study was conducted on 344 children in the same 
      province and two others. Goitre, xerophthalmia (Bitot's spots) and clinical 
      anaemia were observed in 34.2, 0.91 and 18.6% respectively of the children. Most 
      biochemical variables were within the normal range while those of haemoglobin 
      (Hb), mean corpuscular Hb concentration (MCHC) and urinary I excretion were 
      lower, and mean corpuscular volume, mean corpuscular Hb (MCH), and 
      immunoglobulins G and M were higher. Hb was strongly correlated with retinol, 
      ferritin, MCHC, MCH, packed cell volume and erythrocyte count while retinol 
      formed a triad with transthyretin (TTR) and retinol-binding protein (RBP) which 
      were all correlated with one another. Total and free thyroxin and total and free 
      triiodothyronine were positively correlated as were the concentrations of the 
      total and free hormones. Thyrotropin (TSH) was negatively correlated with total 
      and free thyroxin and positively correlated with free triiodothyronine. Thyroxin 
      and triiodothyronine in both free and combined forms were all correlated with 
      thyroxin-binding globulin which in turn was negatively correlated with the triad 
      retinol, RBP and TTR. The triad was also negatively correlated with C-reactive 
      protein. Urinary I excretion was positively associated with total thyroxin and 
      negatively associated with TSH. The anaemia found was not nutritional in origin 
      but due to the effect of infestation with intestinal parasites and malaria.
FAU - Wolde-Gebriel, Z
AU  - Wolde-Gebriel Z
AD  - Ethiopian Nutrition Institute, Addis, Ababa.
FAU - West, C E
AU  - West CE
FAU - Gebru, H
AU  - Gebru H
FAU - Tadesse, A S
AU  - Tadesse AS
FAU - Fisseha, T
AU  - Fisseha T
FAU - Gabre, P
AU  - Gabre P
FAU - Aboye, C
AU  - Aboye C
FAU - Ayana, G
AU  - Ayana G
FAU - Hautvast, J G
AU  - Hautvast JG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Br J Nutr
JT  - The British journal of nutrition
JID - 0372547
RN  - 0 (Hemoglobins)
RN  - 0 (Thyroid Hormones)
RN  - 9679TC07X4 (Iodine)
SB  - IM
MH  - Adolescent
MH  - Age Distribution
MH  - Anemia, Hypochromic/*epidemiology
MH  - Child
MH  - Ethiopia/epidemiology
MH  - Female
MH  - Goiter/*epidemiology
MH  - Hematocrit
MH  - Hemoglobins/analysis
MH  - Humans
MH  - Intestinal Diseases, Parasitic/epidemiology
MH  - Iodine/urine
MH  - Male
MH  - Prevalence
MH  - Sex Distribution
MH  - Thyroid Hormones/blood
MH  - Xerophthalmia/*epidemiology
EDAT- 1993/09/01 00:00
MHDA- 1993/09/01 00:01
CRDT- 1993/09/01 00:00
PHST- 1993/09/01 00:00 [pubmed]
PHST- 1993/09/01 00:01 [medline]
PHST- 1993/09/01 00:00 [entrez]
AID - S0007114593001539 [pii]
AID - 10.1079/bjn19930151 [doi]
PST - ppublish
SO  - Br J Nutr. 1993 Sep;70(2):593-607. doi: 10.1079/bjn19930151.