PMID- 8262223
OWN - NLM
STAT- MEDLINE
DCOM- 19940126
LR  - 20190621
IS  - 0014-5793 (Print)
IS  - 0014-5793 (Linking)
VI  - 336
IP  - 1
DP  - 1993 Dec 20
TI  - Catalytic and activating protons follow different pathways in the H(+)-ATPase of 
      potato tuber mitochondria.
PG  - 83-6
AB  - The effect of some F0F1 inhibitors on the activation of the H(+)-ATPase by the 
      electrochemical proton gradient was investigated in mitochondria extracted from 
      potato tubers. Transient activated state of the ATPase was revealed by addition 
      of ATP and of the detergent lauryldimethylamine oxide (LDAO) to energized 
      mitochondria. Venturicidin, tri-n-butyltin and aurovertin at high concentrations 
      did not affect the process of delta mu H(+)-activation, whereas oligomycin fully 
      blocked it. The results support the idea of separate pathways or binding sites 
      for catalytic and activating protons.
FAU - Valerio, M
AU  - Valerio M
AD  - Biosytemes Membranaires (ERS 30), CNRS, 91198 Gif-sur-Yvette, France.
FAU - Haraux, F
AU  - Haraux F
LA  - eng
PT  - Journal Article
PL  - England
TA  - FEBS Lett
JT  - FEBS letters
JID - 0155157
RN  - 0 (Aurovertins)
RN  - 0 (Detergents)
RN  - 0 (Dimethylamines)
RN  - 0 (Oligomycins)
RN  - 0 (Protons)
RN  - 0 (Trialkyltin Compounds)
RN  - 0 (Venturicidins)
RN  - 4F6FC4MI8W (dodecyldimethylamine oxide)
RN  - 4XDX163P3D (tributyltin)
RN  - EC 3.6.3.14 (Proton-Translocating ATPases)
SB  - IM
MH  - Aurovertins/antagonists & inhibitors/pharmacology
MH  - Catalysis
MH  - Detergents/pharmacology
MH  - Dimethylamines/pharmacology
MH  - Enzyme Activation/drug effects
MH  - Mitochondria/*enzymology
MH  - Oligomycins/antagonists & inhibitors/pharmacology
MH  - Proton-Translocating ATPases/antagonists & inhibitors/*metabolism
MH  - Protons
MH  - Solanum tuberosum/*enzymology
MH  - Trialkyltin Compounds/antagonists & inhibitors/pharmacology
MH  - Venturicidins/antagonists & inhibitors/pharmacology
EDAT- 1993/12/20 00:00
MHDA- 1993/12/20 00:01
CRDT- 1993/12/20 00:00
PHST- 1993/12/20 00:00 [pubmed]
PHST- 1993/12/20 00:01 [medline]
PHST- 1993/12/20 00:00 [entrez]
AID - 0014-5793(93)81614-6 [pii]
AID - 10.1016/0014-5793(93)81614-6 [doi]
PST - ppublish
SO  - FEBS Lett. 1993 Dec 20;336(1):83-6. doi: 10.1016/0014-5793(93)81614-6.