PMID- 8268285
OWN - NLM
STAT- MEDLINE
DCOM- 19940201
LR  - 20191210
IS  - 1044-3983 (Print)
IS  - 1044-3983 (Linking)
VI  - 4
IP  - 6
DP  - 1993 Nov
TI  - Maternal prior pregnancy loss and the sex ratio among infants with sudden infant 
      death syndrome.
PG  - 549-54
AB  - It has been reported that the offspring of human leukocyte antigen 
      (HLA)-compatible parents may have a high male/female sex ratio. To study the 
      hypothesis that parental HLA compatibility is related to sudden infant death 
      syndrome (SIDS), I conducted a population-based case-control study using 
      1982-1990 linked Washington State birth and death certificate data to compare the 
      sex ratio of SIDS cases and controls. SIDS cases were identified by the 
      International Classification of Diseases, 9th revision, CM code 798.0, on the 
      death certificate, and four controls born in the same year as the case were 
      randomly selected for each case. I categorized the infants according to maternal 
      parity and history of pregnancy loss. There was a high risk of SIDS in males 
      relative to females among first liveborn infants whose mothers had had two or 
      more prior pregnancy losses (odds ratio = 7.6, 95% confidence interval = 1.5-39). 
      I had hypothesized a priori that this group would have the largest proportion of 
      infants of HLA-compatible parents. No similar association was observed among 
      infants with a prior liveborn sibling. In addition to the findings from two 
      previous studies, this finding provides further evidence that parental HLA 
      compatibility may be related to the risk of SIDS in offspring.
FAU - Li, D K
AU  - Li DK
AD  - Department of Epidemiology, University of Washington, Seattle.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Epidemiology
JT  - Epidemiology (Cambridge, Mass.)
JID - 9009644
RN  - 0 (HLA Antigens)
SB  - IM
MH  - Abortion, Spontaneous/*epidemiology
MH  - Adult
MH  - Case-Control Studies
MH  - Confounding Factors, Epidemiologic
MH  - Female
MH  - Gestational Age
MH  - HLA Antigens
MH  - Histocompatibility Testing
MH  - Humans
MH  - Infant, Newborn
MH  - Male
MH  - Odds Ratio
MH  - Pregnancy
MH  - Risk Factors
MH  - *Sex Ratio
MH  - Sudden Infant Death/*epidemiology
MH  - Washington/epidemiology
EDAT- 1993/11/01 00:00
MHDA- 1993/11/01 00:01
CRDT- 1993/11/01 00:00
PHST- 1993/11/01 00:00 [pubmed]
PHST- 1993/11/01 00:01 [medline]
PHST- 1993/11/01 00:00 [entrez]
AID - 10.1097/00001648-199311000-00012 [doi]
PST - ppublish
SO  - Epidemiology. 1993 Nov;4(6):549-54. doi: 10.1097/00001648-199311000-00012.