PMID- 8275562
OWN - NLM
STAT- MEDLINE
DCOM- 19940207
LR  - 20190816
IS  - 0009-9163 (Print)
IS  - 0009-9163 (Linking)
VI  - 44
IP  - 2
DP  - 1993 Aug
TI  - Infertility in carriers of two bisatellited marker chromosomes.
PG  - 71-5
AB  - Two unrelated sterile patients, a male and a female, with karyotypes 
      characterized by the presence of two supernumerary bisatellited marker 
      chromosomes, were studied with the aid of fluorescence in situ hybridization 
      (FISH). Using alphoid centromeric specific probes, the markers were identified as 
      an idic (15) (pter-q11) and a mar (14). In both cases a single accessory 
      bisatellited marker was present in the karyotype of one of the parents. A 
      possible correlation between the excess of constitutive heterochromatin and 
      meiotic disturbances in the two patients is discussed.
FAU - Gentile, M
AU  - Gentile M
AD  - IRCCS DeBellis Castellana, Bari, Italy.
FAU - Susca, F
AU  - Susca F
FAU - Resta, N
AU  - Resta N
FAU - Stella, A
AU  - Stella A
FAU - Cascone, A
AU  - Cascone A
FAU - Guanti, G
AU  - Guanti G
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Denmark
TA  - Clin Genet
JT  - Clinical genetics
JID - 0253664
RN  - 0 (Genetic Markers)
SB  - IM
MH  - Adult
MH  - Cells, Cultured
MH  - *Chromosome Aberrations
MH  - Female
MH  - Genetic Markers
MH  - *Heterozygote
MH  - Humans
MH  - Infertility, Female/*genetics
MH  - Infertility, Male/*genetics
MH  - Karyotyping
MH  - Male
MH  - Phenotype
EDAT- 1993/08/01 00:00
MHDA- 1993/08/01 00:01
CRDT- 1993/08/01 00:00
PHST- 1993/08/01 00:00 [pubmed]
PHST- 1993/08/01 00:01 [medline]
PHST- 1993/08/01 00:00 [entrez]
AID - 10.1111/j.1399-0004.1993.tb03849.x [doi]
PST - ppublish
SO  - Clin Genet. 1993 Aug;44(2):71-5. doi: 10.1111/j.1399-0004.1993.tb03849.x.