PMID- 8281514 OWN - NLM STAT- MEDLINE DCOM- 19940215 LR - 20190816 IS - 0165-4608 (Print) IS - 0165-4608 (Linking) VI - 71 IP - 2 DP - 1993 Dec TI - A new approach in the diagnosis and follow-up of bladder cancer. FISH analysis of urine, bladder washings, and tumors. PG - 105-18 AB - The aim of the present study was to ascertain whether fluorescence in situ hybridization (FISH) of urine could be a useful approach in bladder cancer. Herein, we present the cytogenetic and FISH findings in patients with and without bladder cancer. The samples examined with FISH consisted of urine, bladder washings, and tumor tissue, when available. The results obtained show that the FISH technique, particularly when used on urine, is a very useful tool in the diagnosis, early detection, and management of bladder cancer. FAU - Meloni, A M AU - Meloni AM AD - SBRI of Genetrix, Inc., Scottsdale, Arizona 85251. FAU - Peier, A M AU - Peier AM FAU - Haddad, F S AU - Haddad FS FAU - Powell, I J AU - Powell IJ FAU - Block, A W AU - Block AW FAU - Huben, R P AU - Huben RP FAU - Todd, I AU - Todd I FAU - Potter, W AU - Potter W FAU - Sandberg, A A AU - Sandberg AA LA - eng PT - Clinical Trial PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Cancer Genet Cytogenet JT - Cancer genetics and cytogenetics JID - 7909240 RN - 0 (DNA Probes) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Aneuploidy MH - Carcinoma in Situ/diagnosis/genetics/urine MH - Carcinoma, Transitional Cell/*diagnosis/genetics/urine MH - Centromere MH - Chromosome Aberrations MH - DNA Probes MH - Female MH - Humans MH - *In Situ Hybridization, Fluorescence MH - Karyotyping MH - Male MH - Middle Aged MH - Neoplasm Recurrence, Local/diagnosis/genetics/urine MH - Sensitivity and Specificity MH - Therapeutic Irrigation MH - Urinalysis/*methods MH - Urinary Bladder Neoplasms/*diagnosis/*genetics/urine MH - Urine/cytology EDAT- 1993/12/01 00:00 MHDA- 1993/12/01 00:01 CRDT- 1993/12/01 00:00 PHST- 1993/12/01 00:00 [pubmed] PHST- 1993/12/01 00:01 [medline] PHST- 1993/12/01 00:00 [entrez] AID - 0165-4608(93)90015-E [pii] AID - 10.1016/0165-4608(93)90015-e [doi] PST - ppublish SO - Cancer Genet Cytogenet. 1993 Dec;71(2):105-18. doi: 10.1016/0165-4608(93)90015-e.