PMID- 8291026
OWN - NLM
STAT- MEDLINE
DCOM- 19940224
LR  - 20191023
IS  - 0740-7750 (Print)
IS  - 0740-7750 (Linking)
VI  - 19
IP  - 5
DP  - 1993 Sep
TI  - The gene for the iron sulfur protein of succinate dehydrogenase (SDH-IP) maps to 
      human chromosome 1p35-36.1.
PG  - 505-11
AB  - A partial human cDNA clone for the iron-protein (IP) subunit of succinate 
      dehydrogenase (EC 1.3.99.1) was used in Southern analyses of restriction enzyme 
      digests of genomic human and hamster DNA as well as hamster-human hybrids 
      containing a limited number of human chromosomes. The gene for this protein was 
      mapped to human chromosome 1. Digestion of genomic DNA with several restriction 
      enzymes yielded two fragments detectable on a Southern blot, in contrast to the 
      expectations based on the sequence of the cDNA clone. A preliminary analysis of a 
      genomic clone with most of the IP gene has indicated the presence of several 
      introns containing restriction sites detected by the Southern analysis. This 
      genomic clone was also used for subregional mapping by fluorescence in situ 
      hybridization (FISH) to human metaphase chromosomes. A single locus in the region 
      1p35-36.1 was identified.
FAU - Leckschat, S
AU  - Leckschat S
AD  - Department of Biology, University of California, San Diego, La Jolla 92093-0322.
FAU - Ream-Robinson, D
AU  - Ream-Robinson D
FAU - Scheffler, I E
AU  - Scheffler IE
LA  - eng
GR  - GM33752/GM/NIGMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Somat Cell Mol Genet
JT  - Somatic cell and molecular genetics
JID - 8403568
RN  - 0 (Iron-Sulfur Proteins)
RN  - EC 1.3.99.1 (Succinate Dehydrogenase)
SB  - IM
MH  - Animals
MH  - Blotting, Southern
MH  - Cell Line
MH  - Chromosome Mapping
MH  - *Chromosomes, Human, Pair 1
MH  - Cricetinae
MH  - Humans
MH  - Hybrid Cells
MH  - In Situ Hybridization
MH  - Iron-Sulfur Proteins/*genetics
MH  - Succinate Dehydrogenase/*genetics
EDAT- 1993/09/01 00:00
MHDA- 1993/09/01 00:01
CRDT- 1993/09/01 00:00
PHST- 1993/09/01 00:00 [pubmed]
PHST- 1993/09/01 00:01 [medline]
PHST- 1993/09/01 00:00 [entrez]
AID - 10.1007/BF01233256 [doi]
PST - ppublish
SO  - Somat Cell Mol Genet. 1993 Sep;19(5):505-11. doi: 10.1007/BF01233256.