PMID- 8297032 OWN - NLM STAT- MEDLINE DCOM- 19940302 LR - 20190717 IS - 0003-2700 (Print) IS - 0003-2700 (Linking) VI - 65 IP - 23 DP - 1993 Dec 1 TI - Development of techniques for the isolation of iron from biological material for measurement of isotope ratios by fast atom bombardment mass spectrometry. PG - 3501-4 AB - Stable isotopes have gained prominence in nutrition and trace element research. Fast atom bombardment mass spectrometry (FAB-MS) measurement of iron isotope ratios has an accuracy of > or equal to 99.7% with the stable isotopes (54)Fe, (56)Fe, and (58)Fe with relative standard deviations (RSDs) of < or equal to 0.9%. The isolation of iron from biological matrices can be accomplished in 4 h with almost total removal of isobaric interferences caused by (39)KOH, (39)K.H2O, (40)CaOH, and/or (40)Ca.H2O. FAB-MS isotope enrichment measurements from this method compare favorably to predicted absorption/enrichment levels. FAU - Flory, D R AU - Flory DR AD - Department of Pharmacology, University of Colorado Health Sciences Center, Denver 80262. FAU - Miller, L V AU - Miller LV FAU - Fennessey, P V AU - Fennessey PV LA - eng PT - Journal Article PL - United States TA - Anal Chem JT - Analytical chemistry JID - 0370536 RN - 0 (Iron Isotopes) RN - E1UOL152H7 (Iron) SB - IM MH - Erythrocytes/*chemistry MH - Humans MH - Iron/administration & dosage/*blood/isolation & purification MH - *Iron Isotopes MH - Spectrometry, Mass, Fast Atom Bombardment/*methods EDAT- 1993/12/01 00:00 MHDA- 1993/12/01 00:01 CRDT- 1993/12/01 00:00 PHST- 1993/12/01 00:00 [pubmed] PHST- 1993/12/01 00:01 [medline] PHST- 1993/12/01 00:00 [entrez] AID - 10.1021/ac00071a029 [doi] PST - ppublish SO - Anal Chem. 1993 Dec 1;65(23):3501-4. doi: 10.1021/ac00071a029.