PMID- 8297834
OWN - NLM
STAT- MEDLINE
DCOM- 19940310
LR  - 20190920
IS  - 0920-5063 (Print)
IS  - 0920-5063 (Linking)
VI  - 5
IP  - 1-2
DP  - 1993
TI  - A novel biomaterial: poly(dimethylsiloxane)-polyamide multiblock copolymer I. 
      Synthesis and evaluation of blood compatibility.
PG  - 89-98
AB  - Aramid-silicone resins (PASs) consisting of aromatic polyamide (aramid) and 
      poly(dimethyl-siloxane) (PDMS) segments were synthesized by low temperature 
      solution polycondensation. For the evaluation of blood compatibility in vitro, 
      two kinds of experiments were carried out. One was the thromboxane B2(TXB2) 
      release test from platelets attaching to PAS and Biomer. The other was the 
      observation of the platelet adhesion on the surfaces of PAS by scanning electron 
      microscopy (SEM). The results indicated that PAS was bio-inert in vitro. The 
      surface chemical composition of PAS films was investigated by means of electron 
      probe micro analysis (EPMA), X-ray photoelectron spectroscopy (XPS), and dynamic 
      contact angle measurements. The relationship between blood compatibility and 
      surface composition of PAS is discussed.
FAU - Furuzono, T
AU  - Furuzono T
AD  - Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering, 
      Kagoshima University, Japan.
FAU - Yashima, E
AU  - Yashima E
FAU - Kishida, A
AU  - Kishida A
FAU - Maruyama, I
AU  - Maruyama I
FAU - Matsumoto, T
AU  - Matsumoto T
FAU - Akashi, M
AU  - Akashi M
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Biomater Sci Polym Ed
JT  - Journal of biomaterials science. Polymer edition
JID - 9007393
RN  - 0 (Biocompatible Materials)
RN  - 0 (Dimethylpolysiloxanes)
RN  - 0 (Nylons)
RN  - 0 (poly(dimethylsiloxane)-polyamide copolymer)
RN  - 54397-85-2 (Thromboxane B2)
SB  - IM
MH  - *Biocompatible Materials
MH  - Blood Platelets/metabolism
MH  - *Dimethylpolysiloxanes/chemical synthesis
MH  - Humans
MH  - Microscopy, Electron, Scanning
MH  - *Nylons/chemical synthesis
MH  - *Platelet Adhesiveness
MH  - Stress, Mechanical
MH  - Tensile Strength
MH  - Thromboxane B2/blood
EDAT- 1993/01/01 00:00
MHDA- 1993/01/01 00:01
CRDT- 1993/01/01 00:00
PHST- 1993/01/01 00:00 [pubmed]
PHST- 1993/01/01 00:01 [medline]
PHST- 1993/01/01 00:00 [entrez]
AID - 10.1163/156856294x00671 [doi]
PST - ppublish
SO  - J Biomater Sci Polym Ed. 1993;5(1-2):89-98. doi: 10.1163/156856294x00671.