PMID- 8298903 OWN - NLM STAT- MEDLINE DCOM- 19940308 LR - 20190719 IS - 0007-1331 (Print) IS - 0007-1331 (Linking) VI - 73 IP - 1 DP - 1994 Jan TI - Xanthogranulomatous pyelonephritis in childhood: pre-operative diagnosis is possible. PG - 83-6 AB - OBJECTIVE: To diagnose xanthogranulomatous pyelonephritis (XGP) in childhood pre-operatively. PATIENTS AND METHODS: Eleven cases of XGP presenting to Birmingham Children's Hospital over a 10-year-period are reported. Nine (82%) were diagnosed preoperatively on the clinical and radiological findings. RESULTS: The characteristic clinical findings were urinary tract infection (9 cases), palpable renal mass (8 cases) and anaemia (8 cases). The most common radiological findings were enlarged kidney (9 cases), renal calculi (7 cases) and non-functioning kidney (6 cases). Renal ultrasound typically demonstrated a central echoic area (6 cases) and multiple hypoechoic areas in the parenchyma (7 cases). A computed tomography (CT) scan was performed in three cases. This showed characteristic multiple, low attenuation, unenhanced areas within the parenchyma with extension of the inflammatory process into peri-nephric fat (two cases). Ten cases (91%) were of the diffuse type. There was extension into the peri-nephric fat in eight cases (73%). Three cases (27%) were associated with congenital urological abnormalities. Nephrectomy was performed in 10 cases and a partial nephrectomy in one. CONCLUSION: XGP is uncommon in childhood but should always be considered in the differential diagnosis of renal masses, especially in the presence of anaemia. Nephrectomy usually results in a permanent cure. FAU - Hammadeh, M Y AU - Hammadeh MY AD - Department of Paediatric Surgery, Children's Hospital, Birmingham, UK. FAU - Nicholls, G AU - Nicholls G FAU - Calder, C J AU - Calder CJ FAU - Buick, R G AU - Buick RG FAU - Gornall, P AU - Gornall P FAU - Corkery, J J AU - Corkery JJ LA - eng PT - Journal Article PL - England TA - Br J Urol JT - British journal of urology JID - 15740090R SB - IM MH - Adolescent MH - Child MH - Child, Preschool MH - Female MH - Humans MH - Kidney/abnormalities/pathology MH - Kidney Calculi/complications MH - Male MH - Nephrectomy MH - Pyelonephritis, Xanthogranulomatous/*diagnosis/diagnostic imaging/pathology MH - Radiography MH - Urinary Tract Infections/complications EDAT- 1994/01/01 00:00 MHDA- 1994/01/01 00:01 CRDT- 1994/01/01 00:00 PHST- 1994/01/01 00:00 [pubmed] PHST- 1994/01/01 00:01 [medline] PHST- 1994/01/01 00:00 [entrez] AID - 10.1111/j.1464-410x.1994.tb07461.x [doi] PST - ppublish SO - Br J Urol. 1994 Jan;73(1):83-6. doi: 10.1111/j.1464-410x.1994.tb07461.x.