PMID- 8306727
OWN - NLM
STAT- MEDLINE
DCOM- 19940317
LR  - 20190514
IS  - 0012-3692 (Print)
IS  - 0012-3692 (Linking)
VI  - 105
IP  - 2
DP  - 1994 Feb
TI  - Respiratory muscle strength and hemodynamics in chronic heart failure.
PG  - 355-9
AB  - To examine whether respiratory muscle weakness is associated with cardiac 
      function and/or exercise capacity in chronic heart failure (CHF), 23 patients 
      with CHF were evaluated with respiratory muscle strength, pulmonary function 
      tests, cardiac catheterization, and exercise test. The subjects were divided into 
      three groups on their New York Heart Association (NYHA) functional class. Group A 
      consisted of 13 patients with NYHA functional classification class 3 or 4, group 
      B consisted of 10 patients with NYHA classification class 2, and group C 
      consisted of 15 age-matched normal controls. Respiratory muscle strength was 
      assessed with maximal static inspiratory mouth pressure at residual volume level 
      and expiratory mouth pressure at total lung capacity level (PImax, PEmax, 
      respectively). Pulmonary functions in patients with CHF showed almost normal. 
      PImax in group A was significantly less than that in group B or C, although PImax 
      in group B was not significantly different from that in group C. In the patients 
      with CHF, PImax correlated positively with cardiac index and maximal oxygen 
      consumption (r = 0.460 and r = 0.503, p < 0.05, respectively). These findings 
      suggest that inspiratory muscle strength, which was impaired in patients with 
      severe CHF, may be dependent on cardiac function and may be one of the limiting 
      factors on impaired exercise capacity in the patients with CHF.
FAU - Nishimura, Y
AU  - Nishimura Y
AD  - First Department of Internal Medicine, Kobe University School of Medicine, Japan.
FAU - Maeda, H
AU  - Maeda H
FAU - Tanaka, K
AU  - Tanaka K
FAU - Nakamura, H
AU  - Nakamura H
FAU - Hashimoto, Y
AU  - Hashimoto Y
FAU - Yokoyama, M
AU  - Yokoyama M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Chest
JT  - Chest
JID - 0231335
SB  - IM
MH  - Aged
MH  - Blood Pressure/physiology
MH  - Cardiac Output/physiology
MH  - Exercise Tolerance/*physiology
MH  - Female
MH  - Forced Expiratory Volume/physiology
MH  - Heart/*physiopathology
MH  - Heart Failure/*physiopathology
MH  - Hemodynamics/physiology
MH  - Humans
MH  - Inhalation/physiology
MH  - Male
MH  - Maximal Expiratory Flow Rate/physiology
MH  - Middle Aged
MH  - Muscle Contraction/physiology
MH  - Pressure
MH  - Pulmonary Ventilation/physiology
MH  - Pulmonary Wedge Pressure/physiology
MH  - Residual Volume/physiology
MH  - Respiratory Muscles/*physiopathology
MH  - Total Lung Capacity/physiology
MH  - Vital Capacity/physiology
EDAT- 1994/02/01 00:00
MHDA- 1994/02/01 00:01
CRDT- 1994/02/01 00:00
PHST- 1994/02/01 00:00 [pubmed]
PHST- 1994/02/01 00:01 [medline]
PHST- 1994/02/01 00:00 [entrez]
AID - S0012-3692(16)47366-6 [pii]
AID - 10.1378/chest.105.2.355 [doi]
PST - ppublish
SO  - Chest. 1994 Feb;105(2):355-9. doi: 10.1378/chest.105.2.355.